Raed A. Dweik, MD
Staff

Raed A. Dweik, MD
FACP, FRCP(C), FCCP, FCCM, FAHA

Staff, Department of Pathobiology / Lerner Research Institute
Director, Pulmonary Vascular Program, Pulmonary and Critical Care Medicine / Respiratory Institute
Professor of Medicine, The Cleveland Clinic Lerner College of Medicine of CWRU

  • Department of Pathobiology
  • Lerner Research Institute (NC22)
  • Desk A-90
  • The Cleveland Clinic Foundation
  • 9500 Euclid Avenue
  • Cleveland, Ohio 44195
  • Office (Pulmonary): (216) 445-5763
  • Lab (Pathobiology): (216) 445-6542
  • Lab (Breath Analysis): (216) 445-4365
  • Fax: (216) 445-8160
  • Email: dweikr@ccf.org
  • Fellowship - Cleveland Clinic
    Pulmonary Disease/Critical Care
    Cleveland, OH
    1996
  • Residency - Wright State University
    Internal Medicine
    Dayton, OH
    1993
  • Internship - Miami Valley Hospital
    Internal Medicine
    Dayton, OH
    1990
  • Internship - Jordan University Hospital
    Rotating
    Amman, Jordan
    1989
  • Medical School - University of Jordan Faculty of Medicine
    Amman, Jordan
    1988
  • Internal Medicine- Pulmonary Disease
  • Internal Medicine- Critical Care Medicine
  • Internal Medicine
  • Asthma
  • Chronic beryllium disease
  • Critical care
  • Exhaled markers in lung disease
  • Nitric oxide (NO) in lung physiology and disease
  • Pulmonary hypertension

PubMed Publications


  • Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report.
    Erzurum S, Rounds SI, Stevens T, Aldred M, Aliotta J, Archer SL, Asosingh K, Balaban R, Bauer N, Bhattacharya J, Bogaard H, Choudhary G, Dorn GW, Dweik R, Fagan K, Fallon M, Finkel T, Geraci M, Gladwin MT, Hassoun PM, Humbert M, Kaminski N, Kawut SM, Loscalzo J, McDonald D, McMurtry IF, Newman J, Nicolls M, Rabinovitch M, Shizuru J, Oka M, Polgar P, Rodman D, Schumacker P, Stenmark K, Tuder R, Voelkel N, Sullivan E, Weinshilboum R, Yoder MC, Zhao Y, Gail D, Moore TM
    PubMed:20833821 :: 2010
  • Alterations of the arginine metabolome in asthma.
    Lara A, Khatri SB, Wang Z, Comhair SA, Xu W, Dweik RA, Bodine M, Levison BS, Hammel J, Bleecker E, Busse W, Calhoun WJ, Castro M, Chung KF, Curran-Everett D, Gaston B, Israel E, Jarjour N, Moore W, Peters SP, Teague WG, Wenzel S, Hazen SL, Erzurum SC,
    PubMed:18635886 :: 2008
  • Exhaled breath condensate: methodological recommendations and unresolved questions.
    Horváth I, Hunt J, Barnes PJ, Alving K, Antczak A, Baraldi E, Becher G, van Beurden WJ, Corradi M, Dekhuijzen R, Dweik RA, Dwyer T, Effros R, Erzurum S, Gaston B, Gessner C, Greening A, Ho LP, Hohlfeld J, Jöbsis Q, Laskowski D, Loukides S, Marlin D, Montuschi P, Olin AC, Redington AE, Reinhold P, van Rensen EL, Rubinstein I, Silkoff P, Toren K, Vass G, Vogelberg C, Wirtz H,
    PubMed:16135737 :: 2005

M, Curran-Everett D, Fitzpatrick AM, Gaston B, Jarjour NN, Sorkness R, Calhoun WJ, Chung KF, Comhair SA, Dweik RA, Israel E, Peters SP, Busse WW, Erzurum SC, Bleecker ER; National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Identification of asthma phenotypes using cluster analysis in the severe asthma research program. Am J Respir Crit Care Med. 2010 Feb 15;181(4):315-23.

Dweik RA, Sorkness RL, Wenzel S, Hammel J, Curran-Everett D, Comhair SA, Bleecker E, Busse W, Calhoun WJ, Castro M, Chung KF, Israel E, Jarjour N, Moore W, Peters S, Teague G, Gaston B, Erzurum SC. Use of Exhaled Nitric Oxide Measurement to Identify a Reactive, At-risk Phenotype Among Patients With Asthma. Am J Respir Crit Care Med. 2010 Feb 4.

Laskowski D, Beall CM, Dweik R, Strohl KP, Hutte R, Erzurum SC. Response to Hemmingsson, Horn and Linnarsson article "Measuring exhaled nitric oxide at high altitude" Resp. Physiol. Neurobiol. 167(3), 292-298. Respir Physiol Neurobiol. 2010 Jan 31;170(1):1-2; author reply 3-4.

Farha S, Asosingh K, Laskowski D, Hammel J, Dweik RA, Wiedemann HP, Erzurum SC. Effects of the Menstrual Cycle on Lung Function Variables in Women with Asthma.Am J Respir Crit Care Med. 2009 Jun 11.

Shakoor H, Santacruz JF, Dweik RA. Venous thrombo-embolic disease.Compr Ther. 2009 Spring;35(1):24-36. Review. Aytekin M, Comhair SA, de la Motte C, Bandyopadhyay SK, Farver CF, Hascall VC, Erzurum SC, Dweik RA. High levels of hyaluronan in idiopathic pulmonary arterial hypertension.Am J Physiol Lung Cell Mol Physiol. 2008 Nov;295(5):L789-99.

Lara A, Khatri SB, Wang Z, Comhair SA, Xu W, Dweik RA, Bodine M, Levison BS, Hammel J, Bleecker E, Busse W, Calhoun WJ, Castro M, Chung KF, Curran-Everett D, Gaston B, Israel E, Jarjour N, Moore W, Peters SP, Teague WG, Wenzel S, Hazen SL, Erzurum SC; National Heart, Lung, and Blood Institute's Severe Asthma Research Program. Alterations of the arginine metabolome in asthma.Am J Respir Crit Care Med. 2008 Oct 1;178(7):673-81.

Diaz-Guzman E, Heresi GA, Dweik RA, Minai OA. Long-term experience after transition from parenteral prostanoids to oral agents in patients with pulmonary hypertension.Respir Med. 2008 May;102(5):681-9.

O'Meara D, Mireles-Cabodevila E, Frame F, Hummell AC, Hammel J, Dweik RA, Arroliga AC. Evaluation of delivery of enteral nutrition in critically ill patients receiving mechanical ventilation.Am J Crit Care. 2008 Jan;17(1):53-61.

Grob NM and Dweik RA. Exhaled nitric oxide in asthma. From diagnosis, to monitoring, to screening: are we there yet? Chest 2008;133(4):837-9.

Dweik RA, Laskowski D, Abu-Soud HM, Kaneko FT, Hutte R, Stuehr DJ, Erzurum SC. Nitric oxide synthesis in the lung:  regulation by oxygen through a kinetic    mechanism. Journal of Clinical Investigation 1998; 101: 660-666.

Kaneko FT, Arroliga AC, Dweik RA, Comhair SA, Laskowski D, Oppedisano R, Thomassen MJ, Erzurum SC.  Correlation of nitric oxide reaction products to severity of pulmonary hypertension. Am J Respir Crit Care Med. 1998; 158:917-923.

Dweik RA, Comhair SAA, Gaston B, Thunnissen FBJM, Farver C, Thomassen MJ, Kavuru M, Hammel J, Abu-Soud HM, Erzurum SC.  Nitric Oxide Chemical Events in the Human Airway During the Immediate and Late Antigen-Induced Asthmatic Response.  Proceedings of the National Academy of Sciences (USA) 2001; 98:2622-27.

Dweik RA, Laskowski D, Ozkan M, Farver C, Erzurum SC.  High levels of exhaled nitric oxide (NO) associated with NO synthase III expression in lesional smooth muscle in lymphangioleiomyomatosis.  American Journal of Respiratory Cell and Molecular Biology 2001; 24:414-8.

Dweik RA. Pulmonary hypertension and the search for the selective pulmonary vasodilator. Lancet 2002; 360:886-7.

Culver DA and Dweik RA. Chronic Beryllium Disease. Clinical Pulmonary Medicine 2003; 10: 72-79.

Khatri SB, Hammel J, Kavuru MS, Erzurum SC, and Dweik RA. Temporal association of nitric oxide levels and airflow in asthma after whole lung allergen challenge. Journal of Applied Physiology 2003; 95: 436-440.

Machado RF, Laskowski D, Deffenderfer O, Burch T, Zheng S, Mazzone PJ, Mekhail T, Jennings C, Stoller JK, Pyle J, Duncan J, Dweik RA, Erzurum SC. Detection of Lung Cancer by Sensor Array Analyses of Exhaled Breath. American Journal of Respiratory and Critical Care Medicine. 2005; 171:1286-91.

Dweik RA. Nitric oxide, hypoxia, and superoxide: the good, the bad, and the ugly! Thorax. 2005; 60:265-7.

(Dweik RA, contributing author). ATS/ERS Recommendations for Standardized Procedures for the Online and Offline Measurement of Exhaled Lower Respiratory Nitric Oxide and Nasal Nitric Oxide, 2005. American Journal of Respiratory and Critical Care Medicine. 2005;171:912-30.

(Dweik RA, contributing author). ATS/ERS Task Force on Exhaled Breath Condensate. Exhaled breath condensate: methodological recommendations and unresolved questions. European Respiratory Journal. 2005; 26:523-48.

Gill M, Graff GR, Adler AJ, Dweik RA. Validation study of fractional exhaled nitric oxide measurements using a handheld monitoring device. J Asthma. 2006; 43:731-4.

Dweik RA. The lung in the balance: arginine, methylated arginines, and nitric oxide. Am J Physiol Lung Cell Mol Physiol. 2007; 292:L15-7.

Mazzone PJ, Hammel J, Dweik R, Na J, Czich C, Laskowski D, Mekhail T. Lung Cancer Diagnosis by the Analysis of Exhaled Breath with a Colorimetric Sensor Array. Thorax. 2007; 62:565-8.

Heresi GA and Dweik RA. Pulmonary hypertension: evaluation and management. Comprehensive Therapy. 2007;33:150-61.


  • Listed in "Best Doctors in America": 2005- Present
  • Distinguished Teacher Award Internal Medicine Residency Program: 2000-01, 2003-04, 2004-05, 2006-07, 2007-08. 
  • Teacher of the Year Award Pulmonary Fellowship Program: 2006-2007
  • Cleveland Clinic Foundation Innovator Award 2004
  • Listed in "Guide to America's Top Physicians": Edition 2003
  • Listed in Marquis "Who's Who":
    • In the World: 18th Edition, 2001- to present
    • In America: 55th Edition, 2001- to present
    • In Science and Engineering: 5th Edition, 2000- to present
    • In Medicine and Healthcare: 3rd Edition, 2000- to present