Dr. Fred Hsieh Lab
Fred Hsieh, M.D.
Staff, Department of Pathobiology
Our laboratory is interested in studying the development and function of the mast cell in human diseases, with special emphasis on the contribution of mast cells to allergic pulmonary inflammation.
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June 1st 2010
For unknown reasons, food allergies are on the rise. Fred Hsieh, MD, Pulmonary, Allergy and Critical Care Medicine, comments in the Summer 2010 issue of Cleveland Clinic Magazine. [...]
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December 10th 2009
Fred Hsieh, MD, Pulmonary, Allergy and Critical Care Medicine, was awarded Teacher of the Year for his excellence in resident and fellow education. [...]
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November 25th 2009
Respiratory Exchange, research and news from The Cleveland Clinic Respiratory Institute, features Serpil Erzurum, MD, Daniel Culver, DO, Mitchell Olman, MD, Kenneth McCurry, MD and Fred Hsieh, MD [...]
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January 10th 2009
Dan Culver, DO (Critical Care Medicine), Raed Dweik, MD (Critical Care Medicine), JP Achkar, MD (Gastroenterology), Art McCullough, MD (Hepatology) and Fred Hsieh, MD have all been selected as "Best Doctors in Cleveland" for 2009 [...]
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March 11th 2008
Fred Hsieh, MD has been awarded a 'Howard Hughes Physician Scientist Award'. [...]
Our laboratory is interested in studying the development and function of the mast cell in human diseases, with special emphasis on the contribution of mast cells to allergic pulmonary inflammation.
One current focus is the study of mast-cell tissue heterogeneity to understand the determinants of the reactive mucosal mast-cell phenotype as defined in a model of mast-cell/airway epithelial cell coculture.
Our hope is that by understanding the mechanisms by which mast cells are primed to react at airway mucosal surfaces, we will be able to develop therapeutics that specifically target the mast cells that participate in airway inflammation without interrupting the contribution of mast cells to normal physiologic processes.
Research interest:
- Effector cell function in allergic inflammation
Current programs:
- Mast cell: airway epithelial cell interactions in mucosal inflammation
- Tyrosine kinase inhibition in the treatment of mast cell disorders
- Serpil C. Erzurum, M.D., Chair, Department of Pathobiology, Lerner Research Institute,
The Cleveland Clinic Foundation, Cleveland, OH.
- S. Jahar Haque, Ph.D., Department of Cancer Biology, Lerner Research Institute,
The Cleveland Clinic Foundation, Cleveland, OH.
- Alan E. Lichtin, M.D., Hematology and Oncology, The Cleveland Clinic Foundation,
Cleveland, OH.
- Howard Hughes Medical Institute (HHMI) Physician-Scientist Early Career Award
“Effector Cell Development and Lineage Commitment in Allergic Inflammation”
