Eleni Stylianou, Ph.D.
Staff Scientist

Eleni Stylianou, Ph.D.

Staff Scientist, Department of Pathobiology

  • Department of Pathobiology
  • Lerner Research Institute (NC22)
  • The Cleveland Clinic Foundation
  • 9500 Euclid Avenue
  • Cleveland, Ohio 44195
  • Phone: (216) 445-7156
  • Fax: (216) 636-0104
  • Email:styliae@ccf.org
  • Doctorate - University of Wales College of Medicine, Cardiff University
    Wales, United Kingdom
    1989
  • Undergraduate - University of London
    Biochemistry
    London, United Kingdom
    1985
  • Inflammatory Bowel Disease

PubMed Publications



Townsend AP, Roth S, Williams HE, Stylianou E, Thomas NR. New S-Adenosyl-l-methionine Analogues: Synthesis and Reactivity Studies. Org Lett. 2009 Jun 24.

The prognostic significance of steroid receptor co-regulators in breast cancer: co-repressor NCOR2/SMRT is an independent indicator of poor outcome. Green AR, Burney C, Granger CJ, Paish EC, El-Sheikh S, Rakha EA, Powe DG, Macmillan RD, Ellis IO, Stylianou E. Breast Cancer Res Treat. 2008 Aug;110(3):427-37.

The relationship between intranuclear mobility of the NF-kappaB subunit p65 and its DNA binding affinity. Schaaf MJ, Willetts L, Hayes BP, Maschera B, Stylianou E, Farrow SN. J Biol Chem. 2006 Aug 4;281(31):22409-20.

Selective regulation of ICAM-1 and RANTES gene expression after ICAM-1 ligation on human renal fibroblasts. Blaber R, Stylianou E, Clayton A, Steadman R. J Am Soc Nephrol. 2003 Jan;14(1):116-27.

Regulation of interleukin-8 gene expression after phagocytosis of zymosan by human monocytic cells. Friedland JS, Constantin D, Shaw TC, Stylianou E. J Leukoc Biol. 2001 Sep;70(3):447-54.

Bioflavonoid quercetin inhibits interleukin-1-induced transcriptional expression of monocyte chemoattractant protein-1 in glomerular cells via suppression of nuclear factor-kappaB. Ishikawa Y, Sugiyama H, Stylianou E, Kitamura M. J Am Soc Nephrol. 1999 Nov;10(11):2290-6.

c-Rel and p65 trans-activate the monocyte chemoattractant protein-1 gene in interleukin-1 stimulated mesangial cells. Stylianou E, Nie M, Ueda A, Zhao L. Kidney Int. 1999 Sep;56(3):873-82.

Selective sensitization to tumor necrosis factor-alpha-induced apoptosis by blockade of NF-kappaB in primary glomerular mesangial cells. Sugiyama H, Savill JS, Kitamura M, Zhao L, Stylianou E. J Biol Chem. 1999 Jul 9;274(28):19532-7.

Interleukin-1. Stylianou E, Saklatvala J. Int J Biochem Cell Biol. 1998 Oct;30(10):1075-9. Review.

Interleukin 1-induced phosphorylation of MAD3, the major inhibitor of nuclear factor kappa B of HeLa cells. Interference in signalling by the proteinase inhibitors 3,4-dichloroisocoumarin and tosylphenylalanyl chloromethylketone. Guesdon F, Ikebe T, Stylianou E, Warwick-Davies J, Haskill S, Saklatvala J. Biochem J. 1995 Apr 1;307 (Pt 1):287-95.

Source of peritoneal proteoglycans. Human peritoneal mesothelial cells synthesize and secrete mainly small dermatan sulfate proteoglycans. Yung S, Thomas GJ, Stylianou E, Williams JD, Coles GA, Davies M. Am J Pathol. 1995 Feb;146(2):520-9.

Human peritoneal mesothelial cell prostaglandin synthesis: induction of cyclooxygenase mRNA by peritoneal macrophage-derived cytokines. Topley N, Petersen MM, Mackenzie R, Neubauer A, Stylianou E, Kaever V, Davies M, Coles GA, Jörres A, Williams JD. Kidney Int. 1994 Sep;46(3):900-9.

Interleukin 1 induces NF-kappa B through its type I but not its type II receptor in lymphocytes. Stylianou E, O'Neill LA, Rawlinson L, Edbrooke MR, Woo P, Saklatvala J. J Biol Chem. 1992 Aug 5;267(22):15836-41.

Isolation, culture and characterization of human peritoneal mesothelial cells. Stylianou E, Jenner LA, Davies M, Coles GA, Williams JD. Kidney Int. 1990 Jun;37(6):1563-70.

The interaction of organism, phagocyte and mesothelial cell. Stylianou E, Mackenzie R, Davies M, Coles GA, Williams JD. Contrib Nephrol. 1990;85:30-8. Review.

Proteoglycans of CAPD-dialysate fluid and mesothelium. Davies M, Stylianou E, Yung S, Thomas GJ, Coles GA, Williams JD. Contrib Nephrol. 1990;85:134-41. Review.