Publications and patents are also listed at Google Scholar

If you have difficulty obtaining any of the papers listed here, email Jake.


  1. Dhawan A, Harris AL, Buffa FM and Scott JG. Endogenous miRNA sponges mediate the generation of oscillatory dynamics for a non-coding RNA network
  2. Dhawan A, Scott JG, Harris AL and Buffa FM, Pan-cancer characterisation of microRNA with hallmarks of cancer reveals role of microRNA-mediated downregulation of tumour suppressor genes
  3. Dhawan A, Barberis A, Cheng WC, Domingo E, West C, Maughan T, Scott JG, Harris AL and Buffa FM, sigQC: A procedural approach for standardising the evaluation of gene signatures
  4. Nichol D, Rutter J, Bryant C, Jeavons P, Anderson ARA, Bonomo RA and Scott JG. Collateral sensitivity is contingent on the repeatability of evolution
  5. Kaznatcheev A, Peacock J, Basanta D, Marusyk A and Scott JG., Fibroblasts and alectinib switch the evolutionary games that non-small cell lung cancer plays
  6. Scott JG, Dhawan A, Hjelmeland A, Lathia J, Chumakova A, Hitomi M, Fletcher AG, Maini PK and Anderson ARA, Recasting the cancer stem cell hypothesis: unification using a continuum model of microenvironmental forces
  7. Published, peer-reviewed articles


  8. Wadhwa RR, Williamson DFK, Dhawan A and Scott JG. TDAstats: R pipeline for computing persistent homology in topological data analysis. Journal of Open Source Software
  9. Mirzaev I, Williamson DFK and Scott JG. egtplot: A python package for three strategy evolutionary games. Journal of Open Source Software
  10. Nichol D, Bonomo RA and Scott JG. It's too soon to pull the plug on antibiotic cycling. The Lancet Infectious Disease
  11. Curtis GL, Lawrenz JM, George J, Styron JF, Scott J, Shah C, Shepard DR, Rubin B, Nystrom LM and Mesko NW. Adult soft tissue sarcoma and time to treatment initiation: An analysis of the National Cancer Database. Journal of Surgical Oncology
  12. Kang J, Rancati T, Lee S, Oh JH, Kerns SL, Scott JG, Schwartz R, Kim S, Rosenstein BS. Machine Learning and Radiogenomics: Lessons Learned and Future Directions. Frontiers in Oncology
  13. Alfonso JCL, Parsai S, Joshi N, Godley A, Koyfman SA, Caudell JJ, Fuller CD, Enderling H and Scott JG. Temporally-Feathered Intensity Modulated Radiation Therapy: A technique to reduce normal tissue toxicity. Medical Physics
  14. Yoon N, Vander Velde R, Marusyk A and Scott JG. Optimal Therapy Scheduling Based on a Pair of Collaterally Sensitive Drugs, in press, Bulletin of Mathematical Biology
  15. Ahmed KA, Scott JG, Arrington JA, Naghavi AO, Grass GD, Perez BA, Caudell JJ, Berglund AE, Welsh EA, Eschrich SA, Dilling TJ and Torres-Roca JF. Radiosensitivity of Lung Metastases by Primary Histology and Implications for Stereotactic Body Radiation Therapy Using the Genomically Adjusted Radiation Dose. Journal of Thoracic Oncology
  16. 2017

  17. Ottino-Loffler B, Scott JG, and Strogatz SH, Evolutionary dynamics of incubation periods. eLife 2017;6:e30212.
  18. Zhou M, Scott JG, Chaudhury B, Hall L, Goldgof D, Yeom KW, Iv M, Ou Y, Kalpathy-Cramer J, Napel S and Gillies R. Radiomics in Brain Tumor: Image Assessment, Quantitative Feature Descriptors, and Machine-Learning Approaches. American Journal of Neuroradiology (2017)
  19. Karthik N, Ward MC, Scott JG, Mesko N and Shah CS. Factors Associated With Acute and Chronic Wound Complications in Patients With Soft-Tissue Sarcoma With Long-Term Follow-Up. American Journal of Clinical Oncology
  20. Naghavi AO, Gonzalez RJ, Scott JG, Abuodeh YA, Echevarria M, Mullinax JE, Ahmed KA, Harrison LB and Fernandez DC., Staged Reconstruction Brachytherapy Has Lower Overall Cost in Recurrent Soft Tissue Sarcoma. Practical Radiation Oncology
  21. Naghavi AO, Fernandez DC, Mesko N, Juloori A, Martinez A, Scott JG, Shah C and Harrison LB. American Brachytherapy Society consensus statement for soft tissue sarcoma brachytherapy. Brachytherapy
  22. Ottino-Löffler B, Scott JG, and Strogatz SH. Takeover times for a simple model of network infection . Physical Review E
  23. Scott JG and Marusyk A, Somatic clonal evolution: A selection-centric perspective. Biochimica et Biophysica Acta (BBA)-Reviews on Cancer
  24. Kaznatcheev A, Vander Velde R, Scott JG and Basanta D., Cancer treatment scheduling and dynamic heterogeneity in social dilemmas of tumour acidity and vasculature. British Journal of Cancer
  25. Naghavi AO, Gonzalez RJ, Scott JG, Kim Y, Abuodeh YA, Strom TJ, Echevarria M, Mullinax JE, Ahmed KA, Harrison LB and Fernandez DC., Staged reconstruction brachytherapy has lower overall cost in recurrent soft-tissue sarcoma. Journal of contemporary brachytherapy
  26. McFarland CD, Yaglom JA, Wojtkowiak JW, Scott JG, Morse DL, Sherman MY and Mirny L., The damaging effect of passenger mutations on cancer progression. Cancer Research
  27. Grassberger C, Scott JG and Paganetti H., Biomathematical Optimization of Radiation Therapy in the Era of Targeted Agents. International Journal of Radiation Oncology
  28. Dhawan A, Nichol D, Kinose F, Abazeed ME, Marusyk A, Haura EB and Scott JG., Collateral sensitivity networks reveal evolutionary instability and novel treatment strategies in ALK mutated non-small cell lung cancer. Scientific Reports
  29. 2016

  30. Perni S, Mohamed AS, Scott JG, Enderling H, Garden AS, Gunn GB, Rosenthal DI and Fuller CD, CT-based volumetric tumor growth velocity: A novel imaging prognostic indicator in oropharyngeal cancer patients receiving radiotherapy. Oral oncology
  31. Farhidzadeh H, Goldgof DB, Hall LO, Scott JG, Gatenby RA, Gillies RJ and Raghavan M., A quantitative histogram-based approach to predict treatment outcome for Soft Tissue Sarcomas using pre-and post-treatment MRIs. 2016 IEEE International Conference on Systems, Man, and Cybernetics (SMC) (2016)
  32. Rietman, EA, Scott JG, Tuszynski JA and Klement GL., Personalized anticancer therapy selection using molecular landscape topology and thermodynamics. Oncotarget
  33. Naghavi AO, Gonzalez RJ, Scott JG, Mullinax JE, Abuodeh YA, Kim Y, Binitie O, Ahmed KA, Bui MM, Saini AS, and Zager JS and Fernandez DC., Implications of staged reconstruction and adjuvant brachytherapy in the treatment of recurrent soft tissue sarcoma. Brachytherapy
  34. Werner B, Scott JG, Sottoriva A, Anderson ARA, Traulsen A and Altrock PM., The cancer stem cell fraction in hierarchically organized tumors can be estimated using mathematical modeling and patient-specific treatment trajectories. Cancer research
  35. Farhidzadeh H, Kim JY, Scott JG, Goldgof DB, Hall LO and Harrison LB., Classification of progression free survival with nasopharyngeal carcinoma tumors . Proc. SPIE, Medical Imaging
  36. Farhidzadeh H, Chaudhury B, Scott JG, Goldgof DB, Hall LO, Gatenby RA, Gillies RJ and Raghavan M., Signal intensity analysis of ecological defined habitat in soft tissue sarcomas to predict metastasis development. , Proc. SPIE, Medical Imaging
  37. Scott JG, Fletcher AG, Anderson ARA and Maini PK., Spatial metrics of tumour vascular organisation predict radiation efficacy in a computational model. , PLoS Computational Biology
  38. Scott JG, Berglund A, Schell MJ, Mihaylov I, Fulp WJ, Yue B, Welsh E, Caudell JJ, Ahmed K, Strom TS and Mellon E and Torres-Roca JT. A genome-based model for adjusting radiotherapy dose (GARD): a retrospective, cohort-based study. The Lancet Oncology
  39. 2015

  40. Nichol D, Jeavons P, Fletcher AG, Bonomo RA, Maini PK, Paul JL, Gatenby RA, Anderson ARA and Scott, JG. Steering evolution with sequential therapy to prevent the emergence of bacterial antibiotic resistance. PLoS Computational Biology
  41. Kaznatcheev A, Scott JG and Basanta D. Edge effects in game-theoretic dynamics of spatially structured tumours. Proceedings of the Royal Society: Interface
  42. Arora D, Frakes J, Scott JG, Opp D, Johnson C, Song J and Harris E. Incidental radiation to uninvolved internal mammary lymph nodes in breast cancer. Breast cancer research and treatment
  43. 2014

  44. Gallaher J, Cook LM, Gupta S, Araujo A, Dhillon J, Park JY, Scott JG, Pow-Sang J, Basanta D and Lynch CC. Improving treatment strategies for patients with metastatic castrate resistant prostate cancer through personalized computational modeling. Clinical and experimental metastasis
  45. Scott JG, Fletcher AG, Maini PK, Anderson ARA and Gerlee P. A filter-flow perspective of haematogenous metastasis offers a non-genetic paradigm for personalised cancer therapy. European journal of cancer
  46. Baldock AL, Yagle K, Born DE, Ahn S, Trister AD, Neal M, Johnston SK, Bridge CA, Basanta D, Scott JG, Malone H and Swanson KR. Invasion and proliferation kinetics in enhancing gliomas predict IDH1 mutation status. Neuro Oncology
  47. Scott JG, Hjelmeland AB, Chinnaiyan P, Anderson ARA, Basanta D. Microenvironmental variables must influence intrinsic phenotypic parameters of cancer stem cells to affect tumourigenicity. PLoS Computational Biology
  48. 2013

  49. Belmonte-Beitia SJ, Woolley TE, Scott JG, Maini PK and Gaffney EA. Modelling biological invasions: individual to population scales at interfaces. Journal of Theoretical Biology
  50. Scott JG, Basanta D, Anderson ARA and Gerlee P. A mathematical model of tumour self-seeding reveals secondary metastatic deposits as drivers of primary tumour growth. Journal of Theoretical Biology
  51. McTyre E, Scott JG and Chinnaiyan P. Whole brain radiotherapy for brain metastasis. Surgical Neurology International
  52. 2012

  53. Scott JG, Kuhn P and Anderson ARA. Unifying metastasis—integrating intravasation, circulation and end-organ colonization. Nature Reviews Cancer
  54. Scott JG, Bauchet L, Fraum TJ, Nayak L, Cooper AR, Chao ST, Suh JH, Vogelbaum MA, Peereboom DM, Zouaoui S, Mathieu‐Daudé H and Iwamoto F. Recursive partitioning analysis of prognostic factors for glioblastoma patients aged 70 years or older. Cancer
  55. Finkelstein SE, Rodriguez F, Dunn M, Farmello M-J, Smilee R, Janssen W, Kang L, Chuang T, Seigne J, Pow-Sang J, Torres-Roca JF, Heysek R, Biagoli M, Shankar R, Scott JG, Antonia S, Gabrilovich D, Fishman M. Serial assessment of lymphocytes and apoptosis in the prostate during coordinated intraprostatic dendritic cell injection and radiotherapy. Immunotherapy
  56. Scott JG. Phase i trialist. The Lancet Oncology
  57. Basanta D, Scott JG, Fishman MN, Ayala G, Hayward SW and Anderson ARA. Investigating prostate cancer tumour–stroma interactions: clinical and biological insights from an evolutionary game. British Journal of Cancer
  58. Scott JG, Tsai YY, Chinnaiyan P and Yu HHM. Effectiveness of radiotherapy for elderly patients with glioblastoma. International Journal of Radiation Oncology*Biology*Physics
  59. Scott JG, Suh JH, Elson P, Barnett GH, Vogelbaum MA, Peereboom DM, Stevens GHJ, Elinzano H, Chao ST. Aggressive treatment is appropriate for glioblastoma multiforme patients 70 years old or older: a retrospective review of 206 cases. Neuro Oncology
  60. 2011

  61. Basanta D, Scott JG, Rockne R, Swanson KR and Anderson ARA. The role of IDH1 mutated tumour cells in secondary glioblastomas: an evolutionary game theoretical view. Physical Biology
  62. 2010

  63. Packer CD, Carnell RC, Tomcho PM and Scott JG. Development of a four-day service-learning rotation for third-year medical students. Teaching and Learning in Medicine
  64. 2009

  65. Oh S, Scott JG, Shin DH, Suh TS and Kim S. Measurements of dose discrepancies due to inhomogeneities and radiographic contrast in balloon catheter brachytherapy. Medical Physics
  66. Elias HG, Scott JG, Metheny L, Quereshy FA. Multiple myeloma presenting as mandibular ill-defined radiolucent lesion with numb chin syndrome: a case report. Journal of Oral and Maxillofacial Surgery
  67. 2008

  68. Fening SD, Kovacic J, Kambic H, McLean S, Scott JG and Miniaci A., The Effects of Modified Posterior Tibial Slope on Anterior Cruciate Ligament Strain and Knee Kinematics–A Human Cadaveric Study. Journal of knee surgery
  69. 2007

  70. Scott JG, Lee H, Barsoum W and Van Den Bogert AJ., The effect of tibiofemoral loading on proximal tibiofibular joint motion. Journal of anatomy