Research is multi-disciplinary with a focus to identify and develop novel small molecule probes to allow the investigation of disease mechanism. Through bringing together highly skilled teams of scientists, prudent application of resources and go/no-go milestones, we interrogate both the chemical and biological space of a given preclinical hypothesis.

We de-risk these projects to a position where optimized molecules can reach clinical testing either through licensing, bridge partners, or start-up mechanisms. Our growing project portfolio consists of exciting, high quality projects from a wide range of therapeutic areas, focusing on innovative treatments for patients that are driven by integration and collaboration with Cleveland Clinic’s world leading Institutes.