Seth Corey, MD, MPH
Lerner Research Institute,
9500 Euclid Avenue, Cleveland, Ohio 44195
Phone: (216) 444-2506
According to new findings published in JCI Insight, Departments of Cancer Biology and Pediatric Hematology & Oncology researchers have developed a novel preclinical model of Shwachman-Diamond syndrome (SDS), a rare inherited condition characterized by the inability to digest food properly, low white blood cell count and skeletal abnormalities. SDS is also a leukemia predisposition condition, increasing risk of developing myeloid neoplasia by a thousandfold.