Researchers Find Potential for Repurposing Drug to Target Certain Types of Leukemia Cells
05/19/2022

Drs. Jha and Maciejewski have identified eltrombopag as a potent inhibitor of specific leukemia cells, which could lead to new drugs that target leukemia cells while preserving and expanding normal blood cells.

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MCL1 in the Nucleus Appears to Drive Chemoresistance in Colorectal Cancer
04/25/2022

Dr. Gastman and collaborators have published findings indicating Bcl-xL inhibitors may help overcome this complication.

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Podcast: Vaccine Research for Head and Neck Cancers
04/19/2022

Dr. Natalie Silver joins the Cancer Advances podcast to talk about head and neck cancers and the treatment barriers we are trying to overcome.

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Cleveland Clinic Appoints Key Leadership to Center for Immunotherapy & Precision Immuno-Oncology
03/15/2022

J. Joseph Melenhorst, PhD, has been appointed director of the new Cell Therapy and Immuno-Engineering Program, and Vice Chair of the Center for Immunotherapy and Precision Immuno-Oncology at Cleveland Clinic.

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New Model May Predict Immunotherapy Response in Melanoma Patients
03/02/2022

Dr. Gastman’s team found that high levels of a CD8 T-cell subpopulation may predict immune checkpoint inhibitor therapy resistance in melanoma.

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Machine Learning Model Uses Clinical and Genomic Data to Predict Immunotherapy Effectiveness
11/02/2021

With further validation, the tool developed by Dr. Chan may help oncologists better identify patients most likely to benefit from immune checkpoint blockade therapy.

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Cleveland Clinic Joins Multi-site Study and International Network to Study Parkinson’s Disease
10/14/2020

Dr. Chan will serve as the core investigator at Cleveland Clinic, one of four institutions working together as part of this collaborative study funded through Aligning Science Across Parkinson’s.

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VIDEO: New Center for Immunotherapy and Precision Immuno-Oncology to Help Advance Head and Neck Cancer Research
09/28/2020

Researchers from the new Center for Immunotherapy and Precision Immuno-Oncology will leverage their expertise with Cleveland Clinic’s world-class resources to help advance patient care and research into new therapies related to many cancer types, including head and neck cancers.

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Cleveland Clinic Names Chair of Department of Cancer Biology
08/10/2020

Jae Jung, PhD, a renowned expert in virus-induced cancers and immunology research, will lead Lerner Research Institute’s Department of Cancer Biology and will also serve as director of Cleveland Clinic’s Center for Global and Emerging Pathogens Research.

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Cleveland Clinic Names Director of Center for Immunotherapy and Precision Immuno-Oncology
04/28/2020

Timothy Chan, MD, PhD, a renowned cancer researcher and a pioneer in using genomics to determine patients’ response to immunotherapies, will lead the newly created center, which exists at the intersection of cancer research, therapeutics and care.

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