Jacob Hill

Research

Community Engagement in the Development of an Abbreviated Mindfulness-Based Cognitive Therapy Intervention for Depression in Older Black Breast Cancer Survivors

This study has three aims: 1) to obtain patient perspectives to adapt the Mindfulness-Based Cognitive Therapy-Brief (MBCT-Brief) intervention for older Black breast cancer survivors with elevated depressive symptoms; 2) to identify barriers and facilitators to participation in mindfulness-based intervention clinical trials in this population; and 3) to establish the feasibility and acceptability of the intervention and explore its preliminary effects on depressive symptoms. The study uses a mixed-methods approach that includes focus groups and a single-arm clinical trial. The research team will work closely with community-based partners and a community advisory board throughout the study. 

A Cross-Sectional Survey on Patient Preferences to Enhance Mindfulness-Based Interventions for Anxiety and Depression: The MIND-MH Study

This study aims to generate data that will guide the development and/or adaptation of effective, scalable, mindfulness-based interventions (MBIs) to support mental health in patients with anxiety and depression. This will be accomplished by conducting a MIND-MH (Mindfulness, Individual Differences and Mental Health) survey in adults ≥18 years old with elevated anxiety and/or depressive symptoms. The MIND-MH survey will: 1) obtain patient perspectives on their current knowledge, interest, access and use of MBIs, and preferences for MBI structure and format; 2) gather suggestions for how MBIs may be adapted to improve relevancy and scalability; and 3) document self-reported psychosocial health outcomes to explore interrelationships between key psychosocial variables to identify predictors of MBI receptivity, use and delivery preferences, and explore correlations between individual differences (e.g., trait mindfulness) and mental health outcomes (e.g., anxiety and depression). 

Comprehensive Evaluation of Integrative Oncology Interest, Access, and Use Among Patients with Early-Onset Colorectal Cancer: A Mixed Methods Study

This study aims to provide the first in-depth examination of integrative oncology (IO) use among young adults with colorectal cancer, generating critical knowledge to inform the development of age-appropriate IO programs and improve supportive care for this underserved population. This will be accomplished by conducting focus groups with early-onset colorectal cancer (EOCRC) patients and clinical providers, which will inform the development of a comprehensive EOCRC IO Survey that will quantify the interest, access, and utilization of IO services among the EOCRC population. 

Tracking Food Intake Using an AI-Powered Dietary Tracking App in Adults with Mild Cognitive Impairment: a Pilot Feasibility Study

This study aims to determine the feasibility and acceptability of implementing app-based diet tracking using the RxFood app to track ultra-processed food intake in older adults with minor cognitive impairment. We will also explore correlations between change in ultra-processed food intake and cognitive impairment among this population. 

Selected Publications

View publications for Jacob Hill, ND, MS, FABNO
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Hill J, Hodsdon W. In utero exposure and breast cancer development: an epigenetic perspective. Journal of Environmental Pathology Toxicology and Oncology. 2014;33(3):239-245. http://www.ncbi.nlm.nih.gov/pubmed/25272062.

Hill J, Hodsdon W, Schor J, McKinney N, Rubin D, Seely D, Parmar G, Birdsall T, Alschuler L, Lamson D, Birdsall S, Zwickey H. Naturopathic oncology modified Delphi panel. Integrative Cancer Therapies. 2016;15(1). doi:10.1177/1534735415589983.

Hill J, Mills C, Li Q, Smith JS. Prevalence of traditional, complementary, and alternative medicine use by cancer patients in low income and lower-middle income countries. Global Public Health. October 2018:1-13. doi:10.1080/17441692.2018.1534254.

Hill J, Seguin R, Phanga T, Manda A, Chikasema M, Gopal S, Smith JSS. Facilitators and barriers to traditional medicine use among cancer patients in Malawi. PLoS One. 2019:14(10): e0223853. https://doi.org/10.1371/journal.pone.0223853.

Lucius K, Hill J. Combining immunotherapy and natural immune stimulants: mechanisms and clinical implications. Journal of Cancer Research and Clinical Oncology. 2019:0(0). doi:10.1007/s00432-018-02830-x.

Hill JD, Cuthel AM, Grudzen CR. Access to Home and Community Health Services for Older Adults with Serious, Life-Limiting Illness: A Study Protocol. American Journal of Hospice and Palliative Medicine. April 2020:104990912092023.

Hill JD, Cuthel AM, Lin P, Grudzen, CR. Primary Palliative Care for Emergency Medicine (PRIM-ER): Applying Form and Function to a Theory-Based Complex Intervention. Contemporary Clin Trials Communications. 2020 Apr 24:18:100570. Doi: 10.1016/j.conctc.2020.100570.

Tan A, Durbin M, Chung FR, Rubin AL, Cuthel AM, McQuilkin JA, Modrek AS, Jamin C, Gavin N, Mann D, Swartz JL, Austrian JS, Testa PA, Hill J, Grudzen CR. Design and implementation of a clinical decision support tool for primary palliative Care for Emergency Medicine (PRIM-ER). BMC Medical Informatics and Decision Making. 2020;20(1). doi:10.1186/s12911-020-1021-7.

Post E, Faurot K, Kadro Z, Hill J, Nguyen C, Asher G, Gaylord S, Corbett A. Patient Perspectives on the Development of a Novel Mobile Health (mHealth) Application for Dietary Supplement Tracking and Reconciliation – A Qualitative Focus Group Study. Global Advances in Health and Medicine. 2022 Jan 27;11:21649561221075268.

Hill J, Seguin R, Manda A, Chikasema M, Vaz O, Li Q, Yang H, Gopal S, Smith JS. Prevalence of traditional, complementary, and alternative medicine (TCAM) among adult cancer patients in Malawi. Cancer Causes and Control. Published online April 13, 2022. doi:10.1007/S10552-022-01563-0.

Hill JD, Schmucker AM, Siman N, Goldfeld KS, Cuthel AM, Chodosh J, Bouillon-Minois JB, Grudzen CR. Emergency and post-emergency care of older adults with Alzheimer's disease/Alzheimer's disease related dementias. Journal of the American Geriatrics Society. 2022 May 25. doi: 10.1111/jgs.17833. PMID: 35612546.

Hill JD, de Forcrand C, Cuthel AM, Adeyemi OJ, Shallcross AJ, Grudzen CR. Emergency provider perspectives on facilitators and barriers to home and community services for older adults with serious life limiting illness: A qualitative study. PLoS One. 2022;17(8). doi:10.1371/JOURNAL.PONE.0270961

Hill JD, Schmucker AM, Siman N, Goldfeld KS, Cuthel AM, Adeyemi OJ, Edwards E, Bouillon-Minois JB, Grudzen CR. Household Income and Older Adult Population Predict Number of Integrative Medicine Providers Around US Hospitals: An Environmental Scan Study. Global Advances in Health and Medicine. 2022; 11:1-10. Doi:10/1177/2164957X221121077.

Kadro ZO, Chilcoat A, Hill J, Kenney S, Nguyen C, Post E, Corbett AH, Asher GN, Faurot K. Healthcare Professional’s Perspectives on Improving Dietary Supplement Documentation in the Electronic Medical Record: Current Challenges and Opportunities to Enhance Quality of Care and Patient Safety. Global Advances in Health and Medicine. 2023;12. doi:10.1177/27536130231215029 

Shallcross AJ, Hill J. Chapter 51-Mindfulness Interventions in the Handbook of Emotion Regulation, Third Edition. Edited by Gross JJ, Ford BQ. Dec 2023. ISBN 1462553036

Zhao N, Cuthel AM, Storms O, Zhang R, Liddicoat Yamarik R, Hill J, Kaur R, Van Allen K, Flannery M, Chang A, Chung F, Randhawa S, Castro Alvarez I, Young-Brinn A, Kizzie-Gillett CL, Rosini D, Isaacs ED, Hopkins E, Chan GK, Booker-Vaughns J, Maguire M, Navarro M, Reddy Pidatala N, Dunn P, Williams P, Galvin R, Batra R, Welsh S, Vaughan W, Bouillon-Minois JB, Grudzen CR. Advancing patient-centered research practices in a multicenter cluster-randomized controlled trial: A thematic analysis of stakeholder engagement in Emergency Medicine Palliative Care Access (EMPallA). BMC Research Involvement and Engagement. 2024

Seng EK, Hill J, Reeder AK, et al. Feasibility, acceptability, and fidelity of remote-delivered abbreviated mindfulness-based cognitive therapy interventions for patients with migraine and depressive symptoms. Headache J Head Face Pain. n/a(n/a). doi:10.1111/head.14857

Grudzen CR, Siman N, Cuthel AM, Oluwaseun A, Liddicoat Yamarik R, Goldfeld KS, PRIM-ER Investigators. Palliative Care Initiated in the Emergency Department: A Cluster Randomized Clinical Trial. JAMA. Published online January 15, 2025. doi:10.1001/jama.2024.23696

Adeyemi O, Hill J, Siman N, Goldfeld K, Cuthel A, Grudzen CR. Acute Care Use and Prognosis in Older Adults Presenting to the Emergency Department. J Pain Symptom Manage. 2025 Jun;69(6):559-568. 

Siwik CJ, Tankha H, Hill JD, et al. Evaluating an Abbreviated Version of Mindfulness-Based Cognitive Therapy Delivered via Telephone or Videoconferencing Compared to Enhanced Usual Care-Treatment for Migraine and Mood (TEAM-M) Study: Protocol for a Three-Arm Multisite Randomized Controlled Feasibility Trial. JMIR Res Protoc. 2026;15:e93627. doi:10.2196/93627