Jacob Hill, ND, MS, FABNO
Associate Staff
Assistant Professor of Medicine
Email: [email protected]
Location: Cleveland Clinic Main Campus
Research
Dr. Hill’s research program centers on integrative and lifestyle medicine clinical trials, with a particular emphasis on integrative oncology and its impact on quality of life and cancer-related outcomes. His work investigates both the clinical effectiveness of integrative modalities and the underlying biological and behavioral mechanisms through which these approaches may influence disease trajectories. Dr. Hill has specific expertise in food-as-medicine and mindfulness-based interventions, and he is committed to developing and rigorously evaluating novel integrative medicine clinical programs. His research prioritizes community-engaged approaches and the inclusion of historically underrepresented populations to ensure that integrative oncology advances are responsive to diverse patient needs.
Biography
Dr. Jacob Hill graduated from The Pennsylvania State University in 2010 with a Bachelor of Science degree in Nutritional Sciences, and the National University of Natural Medicine in 2014 with a dual degree of Doctor of Naturopathic Medicine and Master of Science in Research. Following graduate school, he completed a naturopathic integrative oncology clinical residency at Cancer Treatment Centers of America near Chicago, Illinois, and later achieved board certification as a Fellow of the American Board of Naturopathic Oncology. Following residency, he was the first naturopathic physician to be selected for the NCCIH-T32 Postdoctoral Research Fellowship in Complementary and Integrative Medicine at the University of North Carolina, Chapel Hill. After his fellowship, he was a Research Scientist at New York University Grossman School of Medicine in the Department of Emergency Medicine and Department of Population Health, where he managed multiple studies on palliative care and emergency medicine, as well as mindfulness-based interventions in patients with migraines, epilepsy, and heart disease. He also maintained a private practice for 4 years at Vermont Wellness Medicine and Integrative Oncology. In 2023 he transitioned to the Department of Wellness and Preventive Medicine at Cleveland Clinic and has launched his independent research program.
Education & Professional Highlights
Education
Fellowship – University of North Carolina at Chapel Hill
Integrative Medicine
Chapel Hill, NC USA
2019
Residency – Cancer Treatment Centers of America
Integrative Oncology
Zion, IL USA
2016
Fellowship – National University of Natural Medicine
Naturopathic Medicine/Naturopathy
St. Louis, MO USA
2021–2022
Postdoctoral Training – Washington University School of Medicine in St. Louis
Health Services Research
Portland, OR USA
2014
Graduate School – National University of Natural Medicine
Integrative Medicine Research and Cancer Research
Portland, OR USA
2014
Undergraduate – Penn State University
Nutritional Sciences
Centre County, PA USA
2010
Awards
- New Investigator Award, Society for Integrative Oncology (SIO), 2017
- New Investigator Award, Academic Consortium for Integrative Medicine and Health (ACIMH), 2019
Memberships
- Professional Member, Academic Consortium of Integrative Medicine and Health
- Professional Member, Society for Integrative Oncology
- Professional Member, American Heart Association
Research
Community Engagement in the Development of an Abbreviated Mindfulness-Based Cognitive Therapy Intervention for Depression in Older Black Breast Cancer Survivors
This study aims to identify barriers and facilitators to participation in mindfulness-based intervention (MBI) clinical trials for older (≥65 years old) Black breast cancer survivors (BCS) with elevated depressive symptoms, as well as obtain patient perspectives to adapt the Mindfulness-Based Cognitive Therapy-Brief (MBCT-Brief) intervention for older Black BCS with elevated depressive symptoms. This is accomplished via collaboration with a community advisory board and focus groups with older Black BCS, which will inform the adaptation of the MBCT-Brief intervention that will be used in a subsequent clinical trial that will examine the feasibility, acceptability and preliminary effects of MBCT-Brief on depressive symptoms in older Black BCS.
A Cross-Sectional Survey on Patient Preferences to Enhance Mindfulness-Based Interventions for Anxiety and Depression: The MIND-MH Study
This study aims to generate data that will guide the development and/or adaptation of effective, scalable mindfulness-based interventions (MBIs) to support mental health in patients with anxiety and depression. This will be accomplished by conducting a MIND-MH (Mindfulness, Individual Differences and Mental Health) survey in adults ≥18 years old with elevated anxiety and/or depressive symptoms. The MIND-MH survey will: 1) obtain patient perspectives on the current knowledge, interest, access and use of MBIs, and preferences for MBI structure and format; 2) gather suggestions for how MBIs may be adapted to improve relevancy and scalability; and 3) document self-reported psychosocial health outcomes to explore interrelationships between key psychosocial variables to identify predictors of MBI receptivity, use and delivery preferences, and explore correlations between individual differences (e.g., trait mindfulness) and mental health outcomes (e.g., anxiety and depression).
Selected Publications
View publications for Jacob Hill, ND, MS, FABNO
(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)
Hill Jacob. Acute Care Use and Prognosis in Older Adults Presenting to the Emergency Department. J Pain Symptom Manage. 2025. 39892477.
Hill Jacob. Palliative Care Initiated in the Emergency Department: A Cluster Randomized Clinical Trial. JAMA. 2025. 39813042.
Hill Jacob, Shallcross Amanda J. Feasibility, acceptability, and fidelity of remote-delivered abbreviated mindfulness-based cognitive therapy interventions for patients with migraine and depressive symptoms. Headache. 2025. 39400343.
. Advancing patient-centered research practices in a pragmatic patient-level randomized clinical trial: A thematic analysis of stakeholder engagement in Emergency Medicine Palliative Care Access (EMPallA). Res Involv Engagem. 2024. 38263088.
Hill Jacob. Healthcare Professionals' Perspectives on Improving Dietary Supplement Documentation in the Electronic Medical Record: Current Challenges and Opportunities to Enhance Quality of Care and Patient Safety. Glob Adv Integr Med Health. 2023. 38130392.