About Us
The SomaScan & Biomarker Core provides cutting edge SomaScan 7k and 11k Proteomic Platforms (SomaLogic), empowering researchers at Cleveland Clinic and across the country to perform targeted proteomics assays on plasma, serum, urine, and other matrices.
As the only facility in Northeast Ohio offering these advanced platforms, we provide unparalleled access to SomaLogic technology, with the closest authorized site being in Maryland.
Our platform delivers state‑of‑the‑art protein measurement and detection to achieve rapid, cost‑effective analysis through a suite of advanced, performance‑driven capabilities:
- Multiplexity: Measures 7,000 or 11,000 human proteins simultaneously, covering approximately half of the genetically encoded human proteome.
- Sensitivity: Detects protein concentrations spanning a dynamic range from femtomolar (10⁻¹⁵) to micromolar (10⁻³) levels.
- Versatility: Accommodates a diverse array of sample types including blood, serum, saliva, plasma, urine, bone marrow aspirate and cell lysate, from both human and nonhuman sources.
- Efficiency: Requires minimal sample volumes, operating effectively with inputs ranging from 55 µL to 550 µL depending on sample type
Please contact [email protected] for further inquiries. If you would like to generate a quote for services, please visit the iLab webpage.
Contacts
Maria Khrestian, MS
Lead Research Technologist
[email protected]
Maria Khrestian completed her Bachelor’s degree in Biology at CWRU and her Master’s degree in Neuroscience at SUNY Buffalo. Her primary responsibility in the Bekris Lab is running their CSF and plasma biomarker assays. Outside of work, she is a huge Cleveland sports fan and enjoys exploring the National Parks.
Services
We currently provide SomaScan 7k and 11k Plasma Proteomics Assays to measure thousands of proteins from every biological pathway without bias. We offer panels of seven (v4.1) and eleven (v5.0) thousand proteins, respectively.
Our core also provides a suite of a la carte targeted protein and biomarker assays including MSD, Luminex and more to analyze molecules of interest.
Equipment
We have the following platforms and equipment available for use:
- TECAN Robot
- Agilant Scanner
- Quanterix SR-X
- MSD Quickplex SQ 120MM
- Luminex 200