Faculty 3

Date Contact Description
12/01/2020 Sara Tavakoli, PhD
tavakos@ccf.org

Flow Cytometry Director
Cleveland Clinic Florida Research & Innovation Center

Job Profile Summary:

This position requires advanced technical and scientific expertise in flow cytometry and cell sorting, and the ability to work collaboratively with investigators in a BSL-2/3 research facility. The candidate will operate all flow cytometry equipment, train users and junior Core staff, consult on experimental design, data analysis, and interpretation and assist with the execution of experiments. This position serves as the leader of the daily Flow Cytometry Core operations and reports to the Director for Shared Resources.

Responsibilities:

  • Operate and manage flow cytometry analyzers and cell sorters, including instrument QA/QC and scheduling.
  • Supervise, mentor, and expertly train junior Core members. ï‚· Train users for application-specific flow cytometry equipment operation in BSL2/3 environment.
  • Advise users on experimental protocols, preparation of samples, analysis, and interpretation of data.
  • Participate in grant and manuscript writing.
  • Establish and maintain a flow cytometry and BSL2/BSL3 biosafety educational program for the user community.
  • Write and implement lab policies and standard operating protocols.
  • Responsible for the proper maintenance, alignment, calibration and troubleshooting of equipment for specific experimental requirements
  • Stay abreast of current best practices and new technological developments in the field.
  • Provide top-level customer service.
  • Provide general oversight for the facility to the Director for Shared Resources.


Work Experience:

  • Demonstrated expertise in polychromatic immunophenotyping and cell sorting, including panel design, equipment operation, data analysis and interpretation, and troubleshooting.
  • Demonstrated ability to advise and guide investigators in multiple research projects, and assist with manuscript and grant writing.
  • Experience in overseeing operations in a Flow Cytometry Facility, and the ability to work independently.
  • Experience in a BSL2/BSL3 environment is highly desirable.
  • Excellent communication and analytical skills.

Education:

  • Ph.D. with at least three years of experience in a Flow Cytometry Core Facility is preferred for an appointment at a Director level.
  • Current ASCP Board Certification for Specialist in Cytometry is highly recommended.

Physical Requirements

  • Visual acuity. The ability to distinguish colors.
  • Manual dexterity to handle specimens and repair equipment.
  • May be required to stand for long periods of time.
  • Light lifting may be required.
  • This position requires candidates to obtain/maintain medical clearance through Cleveland Clinic’s Occupational Health Department to work in a Biosafety Level 3 Environment (BSL3). Medical clearance including medical management is completed upon hire, transfer, and annually. This includes but is not limited to requirements for wearing respiratory protection.

Personal Protective Equipment:

  • Follows standard precautions using personal protective equipment as required
  • Ensures compliance and safety standards for BSL-2/3 environment

Please send all inquiries/CV to:

Sara Tavakoli, PhD
Director Shared Resource Laboratories
Cleveland Clinic
Florida Research and Innovation Center
Port St. Lucie, FL
tavakos@ccf.org

10/15/2020 Sara Tavakoli, PhD
tavakos@ccf.org

Virology Senior Scientist
Cleveland Clinic Florida Research & Innovation Center

The Cleveland Clinic Florida Research and Innovation Center (FRIC) is dedicated to the discovery and advancement of innovative translational research, focused on immuno-oncology and infectious diseases.  The building has 3 floors with approximately 100,000 sq. ft. of dedicated research and support spaces.  The FRIC is developing state-of-the-art Shared Resource facilities in Flow Cytometry, Imaging, Bioinformatics, Select Agents and a Vivarium.  Each of these Shared Resource facilities will support the capabilities of the BSL-2 and BSL-3 research facilities, providing scientists access to advanced technologies in both research environments.

Job Profile Name: Virology Senior Scientist

Job Profile Summary:

This position requires advanced technical and scientific expertise in Virology and the ability to work collaboratively with investigators in a BSL-2/3 research facility.  The candidate will assist with the execution of experiments, consult on experimental design, data analysis, and interpretation and train core technical staff. This position serves as the leader of the daily BSL-3/ABSL-3 Scientific Core operations and reports to the Director for Shared Resources.

Responsibilities:

  • Perform standard cell culture, viral cell culture and cell-based assay development
  • Execute viral production protocols, including plating, transfection, harvest, purification, titration
  • Extraction of nucleic acids/proteins for downstream applications
  • Perform flow cytometry cell sorting/analysis
  • Perform live cell imaging experiments
  • Perform viral infection experiments in mice
  • Supervise, mentor, and expertly train junior Core members.
  • Consultation on scientific design and execution of experiments in a high containment environment.
  • Advise users on experimental protocols, preparation of samples, analysis, and interpretation of data.
  • Participate in grant and manuscript writing.
  • Write and implement lab policies and standard operating protocols.
  • Stay abreast of current best practices and new technological developments in the field.
  • Provide general oversight for the facility to the Director for Shared Resources.
  • Other duties as assigned

Work Experience:

  • Demonstrated expertise in cell culture, viral cell culture, plaque assays, molecular biology techniques, required
  • Experience with flow cytometry and imaging, preferred
  • Experience with single cell library generation, preferred
  • Experience with viral infection experiments in the murine model, preferred
  • Demonstrated ability to advise and guide investigators in multiple research projects, and assist with manuscript and grant writing.
  • Experience in overseeing operations in a virology laboratory, and the ability to work independently.
  • Experience in an ABSL2/ABSL3 environment is highly desirable.
  • Excellent communication and analytical skills.

 Education:

  • Ph.D. in a related field with a minimum of 2 years of experience working in a virology laboratory required

Physical Requirements

  • Visual acuity. The ability to distinguish colors.
  • Manual dexterity to handle specimens and repair equipment.
  • May be required to stand for long periods of time
  • Light lifting may be required.
  • This position requires candidates to obtain/maintain medical clearance through Cleveland Clinic’s Occupational Health Department to work in a Biosafety Level 3 Environment (BSL3).  Medical clearance including medical management is completed upon hire, transfer, and annually. This includes but is not limited to requirements for wearing respiratory protection.

Personal Protective Equipment:

  • Follows standard precautions using personal protective equipment as required
  • Ensures compliance and safety standards for BSL-2/3 environment

Please send all inquiries/CV to:

Sara Tavakoli, PhD
Director Shared Resource Laboratories
Cleveland Clinic
Florida Research and Innovation Center
Port St. Lucie, FL
tavakos@ccf.org

08/06/2020 Anne Gambardella
GAMBARA@ccf.org

Faculty Positions in Infectious Diseases
Cleveland Clinic Florida Research and Innovation Center (FRIC), Port St Lucie, FL

The Cleveland Clinic’s Florida Research and Innovation Center (FRIC), Port St. Lucie Florida, invites applications for several full-time positions at the Assistant, Associate or Full faculty level.

Positions will be within the broad field of emerging infectious diseases. All areas of virology/microbiology relevant to human disease are of interest, including molecular mechanisms of pathogenesis, pathogen-host interactions, immune responses to infection, molecular virology/microbiology, vaccinology and antiviral therapies.

Ideal applicants will be creative and collaborative scientists using advanced approaches combining different elements of cell biology, genetics, bioinformatics, biochemistry and in vitro or in vivo models of infection.

The Cleveland Clinic Florida Research and Innovation Center (FRIC) is dedicated to the discovery and advancement of innovative translational research, focused on infectious diseases and immuno-oncology. The Center is an exceptional state-of-the-art facility with approximately 100,000 sq. ft. of dedicated research and support spaces. The FRIC has Shared Resource facilities in Flow Cytometry, Imaging, Bioinformatics, Select Agents and a Vivarium supporting ABSL-3 suites. Faculty at the FRIC will closely collaborate with scientists at the Lerner Research Institute, a network of ~190 labs at Cleveland Clinic’s main campus in Ohio. Faculty at the FRIC will also be encouraged to establish collaborations with physicians at the regional hospitals of Cleveland Clinic Florida.

Key Requirements

The selected candidates will have an outstanding record in infectious diseases/virology or related fields (e.g. immunology). The selected candidates will possess scientific vision, leadership skills and be competitive in acquiring extramural grants. Basic requirements for the positions include a Ph.D. and/or M.D., as well as postdoctoral research experience and a strong record of research accomplishments and publications in the field of infectious diseases/virology or related fields. Candidates for positions at the Associate or Full faculty level will have demonstrated a strong track record of publications and external funding.

Application Instructions

Please apply by sending your CV, a motivation letter, a project description and providing contacts of four potential referees. The project description should be a maximum of 3 pages long and describe both current and future research plans.


Please email application materials to:

Michaela U. Gack, Ph.D.
The Arthur and Marylin Levitt Endowed Chair
Scientific Director
Florida Research and Innovation Center
Port Saint Lucie, FL

Administrative Support:
Anne Gambardella;
Email: GAMBARA@ccf.org



Postdoctoral 1

Date Contact Description
09/02/2020 Michaela Gack
gackm@ccf.org

Individuals with experience in virology, molecular biology, biochemistry, or cell biology are strongly encouraged to send a CV, cover letter, and the contact details of three referees to:

Michaela U. Gack, Ph.D.

The Arthur and Marylin Levitt Endowed Chair
Scientific Director
Florida Research & Innovation Center
9801 SW Discovery Way
Port Saint Lucie, FL 34987

Email: gackm@ccf.org | Phone: 772.345.8114



Technical & Adminstrative

Applications for technical research positions and administrative positions at the Lerner Research Institute can be submitted on the Cleveland Clinic jobs web site.