Dr. Ignacio Mata is seeking a highly motivated Postdoctoral fellow to help develop a neurogenetics program at the Genomic Medicine Institute – Lerner Research Institute of Cleveland Clinic.

The Mata research group (https://www.lerner.ccf.org/gmi/mata/) just moved to the Cleveland Clinic where it will continue his quest to try to understand the genetic component of neurological disorders, in particular Parkinson’s disease (PD), Parkinson’s Disease Dementia (PDD) and Dementia with Lewy Bodies (DLB). Dr. Mata is a world leader in genetic Parkinson research in the Latino population, and is looking for an exceptional candidate to join his PD genetics research program.

The successful candidate will join an interdisciplinary team of computational biologists, bioinformatics analysts (https://sites.google.com/view/lalresearchgroup/) and excellent clinicians who are working together to identify rare and common genetic variants that cause or confer risk to neurological disorders. The candidate will join the Mata lab to perform data analysis and to collaborate with software engineers who are developing computational tools. The responsibilities will include processing and quality control of genetic data sets, as well as statistical analysis of joint analysis of genetic variation and clinical phenotype data.

Applicants should have a recent PhD degreein genomics, computer science, statistics, bioinformatics, or a related field with excellent verbal and written communication skills in English and a proven track record of first-author publications. Experience working with biological datasets and proficiency in at least two of the following technologies: R, Unix, Perl, Python, Java, Matlab, C, C++ and experience in working in HPC and/or cloud-based environment are preferred.

Interested applicants should send a cover letter, CV and 2-3 reference letters to Dr Ignacio Mata at matai@ccf.org.

A postdoctoral fellow position is available in the Genomic Medicine Institute at the Cleveland Clinic Lerner Research Institute. The successful candidate(s) will work in the Bekris lab which is supported by multiple grants and funding resources. Bekris lab research is focused on identifying and evaluating the functional impact of genetic and epigenetic factors in Alzheimer’s disease and other neurodegenerative disorders.

Recent PhDs with a degree in molecular biology or related field as well as a background in experimental genomics and epigenomics utilizing cellular models will be considered. Experience in high-throughput analysis of next-generation sequencing data and familiarity with widely-used genomic/epigenomic databases and related software is a plus.

The candidate must have excellent verbal and written communication skills as well as a publication record. In addition, the candidate must be capable of working within a team of molecular biologists, bioinformaticians, statisticians and clinicians.

Please email your CV, a brief statement of your research interests and three references to 

Dr. Lynn Bekris (bekrisl@ccf.org). 

A Postdoctoral Fellow position is available in the laboratory of Dr. Angela Ting (http://www.lerner.ccf.org/gmi/ting/) at the Cleveland Clinic Lerner Research Institute. Our research focuses on understanding the functional impact of abnormal DNA methylation in cancer. We employ next generation sequencing (NGS) technologies to identify epigenetic changes throughout the genome and carry out mechanistic studies to define the functions of these changes and their impact on the transcriptome and cancer biology. We are particularly interested in developing and testing hypotheses for novel alterations outside of the gene promoter context.

Candidates must have scientific and technical expertise in molecular biology, RNA biology, biochemistry, transcription mechanisms, or gene delivery by transfection and lentivirus. Additional requirements include a Ph.D. degree in biological sciences, a strong publication record, proficiency in spoken and written English, and the ability to work/troubleshoot independently as well as understanding and incorporating findings in the scientific literature into his/her research. The postdoctoral fellow will be expected to take a lead role in data generation, analysis, interpretation, visualization, and manuscript preparation.

Please send your curriculum vitae and contact information for 3 references to Angela Ting (tinga@ccf.org).

A Computational Biology Postdoctoral Fellow position is available in the laboratory of Dr. Angela Ting (http://www.lerner.ccf.org/gmi/ting/) at the Cleveland Clinic Lerner Research Institute. Our research focuses on understanding the functional impact of abnormal DNA methylation in cancer. We employ next generation sequencing (NGS) technologies, including Illumina short reads, PacBio, and Oxford Nanopore, to identify epigenetic changes throughout the genome and carry out mechanistic studies to define the functions of these changes and their impact on the transcriptome and cancer biology. We are particularly interested in developing and testing hypotheses for novel alterations outside of the gene promoter context as well as delineating the origin of aberrant DNA methylation in oncogenesis.

Candidates must have scientific and technical expertise in computational biology, bioinformatics, or systems biology. Preference will be given to those with experience in analysis of next generation sequencing data. Additional requirements include a Ph.D. degree in biological sciences or computer science, a strong publication record, proficiency in spoken and written English, and the ability to work/troubleshoot independently as well as understanding and incorporating findings in the scientific literature into his/her research. The postdoctoral fellow will be expected to take a lead role in data analysis, interpretation, visualization, and manuscript preparation.

Please send your curriculum vitae and contact information for 3 references to Angela Ting (tinga@ccf.org).