Postdoctoral 9

Date Contact Description
04/17/2018 Laura Nagy
nagyl3@ccf.org

A Postdoctoral Fellow position is available in the Cleveland Clinic in the laboratory of Dr. Laura Nagy in the Department of Inflammation and Immunity to study the effects of ethanol on the innate immune system, including toll-like receptor signal transduction and complement activation.  The research will focus on the effects of chronic ethanol on key signal transduction pathways in hepatic innate immune cells (macrophages, infiltrating monocytes, neutrophils, etc) with a goal towards understanding the mechanism of development of chronic inflammatory responses in liverin order to develop rationale therapeutic interventions.  Our recent work using next generation sequencing of miRNA indicates that ethanol targets multiple levels in the regulation of cytokine expression leading to the development of alcoholic liver disease. We are also interested in identifying biomarkersand genetic risk factors for disease severity in a cohort of patients with alcoholic liver disease.

Experience in at least one of the following areas is desired:  cell biology, signal transduction, molecular biology, bioinformatics or macrophage biology. Experience in experimental design and data analysis in both cultured cells and animal models is preferred.  Strong written and oral communication skills are required.

Candidates should have a recent PhD in cell biology, immunology, biochemistry, or a related discipline and experience in signal transduction and cell biology. 

Interested applicants please submit a CV and names and contact information for three references to Dr. Laura Nagy, Department of Inflammation and Immunity (NE40) at Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland OH 44195 or via email to nagyL3@ccf.org

03/27/2018 Srinivasan Dasarathy MD
dasaras@ccf.org

We have an immediate opening for a Postdoctoral Fellow position in the Dr. Dasarathy Laboratory in the Department of Inflammation and Immunity at the Cleveland Clinic Lerner Research Institute. Individuals with experience and interest in studying signal transduction during metabolic perturbations are encouraged to apply. The laboratory focus is on using integrated molecular metabolic approaches in a comprehensive array of cellular, mouse, and human models.

A highly motivated candidate will join a productive research team to participate in NIH funded projects focusing on the molecular mechanisms of skeletal muscle loss and metabolic perturbations in disease. The candidate should have a publication record demonstrating on-hand molecular biology and cell biology expertise.

Must be familiar with mesenchymal cell culture (preferably skeletal muscle), Western blotting, and RNA based methods including quantitative PCR and reporter assays, subcloning between different vectors, lenti- retro- and adenoviral systems for cDNA and shRNA delivery. Preference will be given to candidates with previous experience in skeletal muscle biology, CRISPR/Cas9-dependent gene editing, confocal microscopy/cell imaging or mouse models of muscle loss. Excellent communication skills in English are essential. The appointee will be expected to take advantage of this career opportunity to develop skills in manuscript publication and grantsmanship.

Ph.D. or M.D. with relevant laboratory experience is required. Proficiency in spoken and written English is required.  Send cover letter and CV and contact information for 3 references to: Dr. Srinivasan Dasarathy; Department of Pathobiology; Lerner Research Institute / NE4 208; Cleveland Clinic; 9500 Euclid Avenue; Cleveland, Ohio 44195. (216) 636-0096; E-mail: dasaras@ccf.org.

02/21/2018 Florian Rieder, MD
riederf@ccf.org

We have an opening for a Postdoctoral Fellow position in the Dr. Florian Rieder Laboratory in the Department of Pathobiology at the Cleveland Clinic Lerner Research Institute. Individuals with experience and interest in studying intestinal inflammation and fibrosis and cell to extracellular matrix interactions are encouraged to apply.

A highly motivated candidate will join a productive research team to participate in NIH and industry funded projects focusing on the roles of the extracellular matrix and cell to matrix interactions during tissue inflammation and fibrosis of the intestine. The candidate should have a publication record demonstrating on-hand molecular biology and cell biology expertise.

The candidate should furthermore be familiar with primary human cell culture, Western blotting, and RNA based methods including quantitative PCR and reporter assays, immunohistochemistry and mouse models of gut inflammation. Excellent communication skills in English are essential. The appointee will be expected to take advantage of this career opportunity to develop skills in manuscript publication and grantsmanship.

Ph.D. or M.D. with relevant laboratory experience is required. Proficiency in spoken and written English is required.  Send cover letter and CV and contact information for 3 references to: Dr. Florian Rieder; Department of Pathobiology; Lerner Research Institute / NC22; Cleveland Clinic; 9500 Euclid Avenue; Cleveland, Ohio 44195. (216) 445 7156; E-mail: riederf@ccf.org.

12/11/2017 Feng Lin
linf2@ccf.org

A postdoctoral position is available in the laboratory of Dr. Feng Lin in the Department of Immunology at the Cleveland Clinic Lerner Research Institute.

The ideal candidate will have a strong basic research background as evidenced by recent publications, and a keen interest in inflammation research. Proficiency in common immunological and/or molecular biology techniques − ELISA,  flow cytometry, DNA and protein electrophoresis, western blotting, PCR, transfection and mouse models of human diseases is required. 

 The selected candidate will receive a competitive salary and benefits package, and have access to state-of-the-art core facilities in the Lerner Research Institute, with opportunities for career advancement and multiple avenues for collaboration with clinicians at the Cleveland Clinic. More information about Lin Lab’s research may be found at www.lerner.ccf.org/immuno/lin/. Additional information about postdoctoral training at the Lerner Research Institute is available at www.lerner.ccf.org/education/postdoc/.

 The candidate must have (or be close to finishing) a PhD or MD/PhD degree.

 Highly motivated and qualified individuals should submit a cover letter describing research accomplishments and interests (no more than 2 pages), a CV and contact information for 3 references to Dr. Feng Lin (linf2@ccf.org). 

12/05/2017 Neetu Gupta
guptan@ccf.org

A postdoctoral position is available in the laboratory of Dr. Neetu Gupta in the Department of Immunology at the Cleveland Clinic Lerner Research Institute.

The ideal candidate will have a strong background in lung biology as evidenced by recent publications, and a keen interest in investigating asthma pathology. Proficiency in common immunological and molecular biology techniques − ELISA, multi-color flow cytometry, DNA and protein electrophoresis, western blotting, PCR, transfection − and mouse models of asthma is required. Additional experience in fluorescence microscopy/histology is desirable (but not required). The successful candidate will join a dynamic team of basic and translational immunology researchers to investigate novel regulators of airway inflammation and hyperresponsiveness.

The selected candidate will receive an attractive salary and benefits package, and have access to state-of-the-art core facilities in the Lerner Research Institute, with opportunities for career advancement and multiple avenues for collaboration with clinicians at the Cleveland Clinic. More information about Gupta Lab’s research may be found at www.lerner.ccf.org/immuno/gupta/. Additional information about postdoctoral training at the Lerner Research Institute is available at www.lerner.ccf.org/education/postdoc/.

The candidate must have (or be close to finishing) a PhD or MD/PhD degree. Proficiency in spoken and written English is required.

Highly motivated and qualified individuals should submit a cover letter describing research accomplishments and interests (no more than 2 pages), a CV and contact information for 3 references to Dr. Neetu Gupta (guptan@ccf.org). 

12/04/2017 Neetu Gupta
guptan@ccf.org

A postdoctoral position is immediately available in the laboratory of Dr. Neetu Gupta in the Department of Immunology at the Cleveland Clinic Lerner Research Institute.

The ideal candidate will have a strong background in cellular immunology with deep interest in and understanding of B cell biology and signal transduction as evidenced by recent publications. Proficiency in common immunological and molecular biology techniques (including, but not limited to, ELISA, multi-color flow cytometry, DNA and protein electrophoresis, western blotting, PCR, transfection), and mouse models of disease is required. Additional experience with confocal and/or TIRF microscopy is highly desirable. The successful candidate will join a dynamic team of basic and translational immunology researchers to investigate molecular mechanisms regulating B lymphocyte effector functions in the context of inflammation and autoimmunity.

The selected candidate will receive an attractive salary and benefits package, and have access to state-of-the-art core facilities in the Lerner Research Institute, with opportunities for career advancement and multiple avenues for collaboration with clinicians at the Cleveland Clinic. More information about Gupta Lab’s research may be found at www.lerner.ccf.org/immuno/gupta/. Additional information about postdoctoral training at the Lerner Research Institute is available at www.lerner.ccf.org/education/postdoc/.

The candidate must have (or be close to finishing) a PhD or MD/PhD degree.  Proficiency in spoken and written English is required.

Highly motivated and qualified individuals should submit a cover letter describing research accomplishments and interests (no more than 2 pages), a CV and contact information for 3 references to Dr. Neetu Gupta (guptan@ccf.org). 

08/31/2017 Anna Valujskikh
valujsa@ccf.org

A postdoctoral position is available in Dr. Anna Valujskikh’s lab in the Department of Immunology at the Cleveland Clinic. The research in the lab focuses on the immune responses following transplantation with the objective of developing strategies improving outcomes of solid organ transplants in high risk recipients. The group uses mouse model of heart and renal transplantation and a broad variety of cellular and molecular assays to evaluate alloimmunity. Funded projects investigate T cell reconstitution following lymphoablation in transplant recipients and the mechanisms of alloantibody generation and antibody-mediated rejection of renal allografts.

The candidate should have a PhD or MD/PhD degree, background in cell biology or immunology, a good record of productivity, personal initiative and strong technical and communication skills. 

03/13/2017 Booki Min
minb@ccf.org

The ideal candidate should have a strong background in cellular immunology and/or autoimmunity, with an in-depth understanding of T cell biology, particularly regulatory T cells. Proficiency in common cellular immunological techniques such as flow analysis, adoptive transfer, and molecular biology is required. The successful candidate will engage in an exciting project combining the autoimmunity and regulatory T cell therapy.

The candidate must have completed, or be nearing completion of a PhD, MD, or MD/PhD degree. Proficiency in spoken and written English is required.

To apply please submit a cover letter indicating areas of expertise, a brief statement of research interests, a CV and contact information for 3 reference to Dr. Booki Min (minb@ccf.org). Please express your interest before April 30, 2017.

01/06/2017 Michael Flickinger and Fariba Rezaee
flickim@ccf.org; rezaeef@ccf.org

We have an immediate opening for a Postdoctoral Fellow position in the Dr. Piedimonte/Center for Pediatric Research - Laboratory in the Department of Pathobiology at the Cleveland Clinic Lerner Research Institute. Individuals with experience and knowledge of techniques in all of the above listed technical skills are encouraged to apply.

Must be familiar with cultivation of multiple cell lines, Western blotting, and RNA based methods including quantitative PCR and reporter assays, subcloning between different vectors, lenti- retro- and adenoviral systems of shRNA delivery, expression of exogenous proteins, and the Casp9/Crispr system. Must be familiar with working with rodents, including intratracheal inoculation, isolation of airway cells and immunohistochemistry. In addition, experience in isotope tracer methodologies would be beneficial.  Excellent communication skills in English are essential. The successful candidate will be expected to design, implement and manage research projects addressing cellular response to viral infection and pollutions.  The appointee will be expected to take advantage of this career opportunity to develop skills in manuscript publication and grantsmanship.

Ph.D. or M.D. with relevant laboratory experience and proficiency in spoken and written English are required. Send cover letter and CV and contact information for 3 references to: Dr. Fariba Rezaee; Pediatrics/Department of Pathobiology; Lerner Research Institute / NC22; Cleveland Clinic; 9500 Euclid Avenue; Cleveland, Ohio 44195. (216) 445-0564; rezaeef@ccf.org and flickim@ccf.org.



Technical & Adminstrative

Applications for technical research positions and administrative positions at the Lerner Research Institute can be submitted on the Cleveland Clinic jobs web site.