Location: NE1-205
Title: "Therapeutic treatment of inflammatory diseases and cancer metastasis by regulation of transendothelial migration. "

William Muller, MD, PhD: Northwestern University

Hosted by Rob Fairchild, PhD

Location: NE1-205
Title: "At the Crossroads of IL-17 signaling: Autoimmunity, Fungal Immunity and Beyond"

Sarah Gaffen, PhD, Director of Basic Rheumatology Research, University of Pittsburgh School of Medicine, Pittsburgh PA

Hosted by: Xiaoxia, Li, PhD

Location: NE1-205
Title: TBD

Samreen Jatana - McDonald Lab

Location: NE1-205
Title: Faculty Update

Michelle Longworth, PhD

Location: NE1-205
Title: TBD

Manishkumar Patel - Gupta Lab

Location: NE1-205
Title: "TNF receptor restrains IBD development - the bright side of ytokine signaling"

Brent Polk, MD: Professor of Pediatrics, Pediatric Gastroenterology, Hepatology & Nutrition, Professor of Biochemistry & Molecular Medicine, Vice Dean for Child Health at University of Southern California & Childrens Hospital Los Angeles

Tumor necrosis factor (TNF) has been a successful therapeutic target for Crohn’s disease and ulcerative colitis. And yet, long-term only 35% of patients achieve long term response to anti-TNF therapies. Our laboratory has shown that TNF is an essential pathway in intestinal epithelial repair responses. Our recent findings suggest that the influence on normal development and homeostasis extends to immunologic regulation and the microbiome with high relevance to IBD.  Hosted by Christine McDonald, PhD, and Xiaoxia Li, PhD

Location: NE1-205
Title: TBD

Quang Tam Nguyen - Min Lab

Location: NE1-205
Title: TBD

Beth Moore, PhD: University of Michigan

Location: NE1-205
Title: TBD

Megan Zangara - McDonald Lab

Location: NE1-205
Title: "Dysregulated Gut Microbial Fermentation Induced Cholestatic Liver Cancer"

Vijay Kumar, PhD: University of Toledo

Hosted by Andrei Ivanov, PhD

Location: NE1-205
Title: "Transcriptional and Epigenetic Control of Type II response - the Good and the Bad"

Dorina Avram, PhD: University of Florida

Type II response in asthma and anti-helminth response will be discussed, and its regulation by essential transcription factors.  Hosted by Booki Min, DVM, PhD

Location: NE1-205
Title: "Epigenetic Insights into Severe Pneumonia"

Ben Singer, MD: Northwestern University

Mouse studies determined that DNA methylation governs the identity and function of Foxp3⁺ regulatory T (Treg) cells, which serve an essential role in promoting resolution of acute lung inflammation and repair of lung damage. We developed a flow-cytometric sorting procedure combined with novel biochemical and computational approaches that allow multidimensional assessment of alveolar T cell populations in critically ill patients with severe pneumonia. Using these tools, we determined that human alveolar T cells obtained from the inflamed alveolar microenvironment share the epigenetic and transcriptional landscape predicted by murine experiments. Hosted by Rachel Scheraga, MD

Location: NE1-205
Title: TBD

Emily Tsai, PhD: Columbia University

Hosted by Dennis Stuehr, PhD

Location: NE1-205
Title: TBD

Haitao Zhang - Runge Lab

Location: NE1-205
Title: TBD

Emma Keller - Jorgensen Lab

Location: NE1-205
Title: TBD

Suheyla Hasgur - Valujskikh Lab

Location: NE1-205
Title: "Extracellular Matrix in Inflammation and Immune Regulation"

Paul Bollyky, MD

I am interested in the contributions of pericellular matrix - the coat of proteoglycans, hylauronan, and heparan sulfate that surrounds cells - to immune function. In particular, we are studying how the pericellular matrix contributes to antien presentation, cytolytic killing, and cellular metabolism with a focus on autoimmune diseases such as type 1 diabetes and multiple sclerosis.  We also have an active research program focused on targeting the extracellular matrix to promote immune tolerance.  Hosted by Carol de la Motte, PhD

Location: NE1-205
Title: TBD

Raneem Khedraki - Baldwin Lab

Location: NE1-205
Title: Faculty Update

Takuya Sakaguchi, PhD

Location: NE1-205
Title: TBD

Akansha Jalota - Gupta Lab

Location: NE1-205
Title: Faculty Update

William Baldwin, MD, PhD

Location: NE1-205
Title: TBD

Olivia Stephens - Erzurum Lab

Location: NE1-205
Title: Faculty Update

Jeannette Messer, DVM, PhD

Location: NE1-205
Title: TBD

Satoshi Miyairi - Fairchild Lab

Location: NE1-205
Title: TBD

Constantine Stratakis, PhD: NIH Clinical Center

Hosted by Giovanni Piedimonte, MD

Location: NE1-205
Title: TBD

Susana Lechuga - Ivanov Lab

Location: NE1-205
Title: TBD

Takushi Kurashinge - Fairchild Lab