Cleveland Clinic’s Musculoskeletal Research Center (MSRC), a highly collaborative initiative, is led by Kathleen A. Derwin, PhD (Director), Biomedical Engineering, and Kurt P. Spindler, MD (Co-Director), Orthopaedic Surgery.    Oversight of the MSRC is provided by a Governance Board, and strategic direction is implemented by a Steering Committee. 

MSRC Governance Board

MSRC Steering Committee

The MSRC aims to foster collaboration and growth of Cleveland Clinic’s musculoskeletal research community through a variety of strategic programs and initiatives. These include a pilot projects program, internal grant review program, seminar series, annual retreat, and national/international workshops and conferences, as well as support and development of infrastructure and resources, strategic recruitments, and philanthropic outreach.

We invite interested parties to contact us at the MSRC to learn more about our activities and opportunities for participation.


The center was established in 2001 as the Orthopaedic Research Center. Joseph P. Iannotti, MD, PhD, Orthopaedic Surgery, and Vincent C. Hascall, PhD, Biomedical Engineering, were the first Co-Directors; George F. Muschler, MD, an orthopaedic surgeon and physician-scientist, served as Director from 2005-2013. In 2007, the center was restructured and renamed the Orthopaedic & Rheumatologic Research Centers to reflect the inclusion of musculoskeletal rheumatologic research and the center’s expansion to involve researchers from over a dozen different departments and centers at Cleveland Clinic. The center was rebranded as the MSRC in 2016 to reflect the broad and multidisciplinary aspects of musculoskeletal research ongoing at Cleveland Clinic, spanning orthopaedics, rheumatology, spine, physiatry, imaging, pathology, neurosciences, and biostatistics.