Neurosciences : Seminars

The Department of Neurosciences at Cleveland Clinic's Lerner Research Institute comprises a group of internationally recognized scientists who are committed to understanding the mechanisms of brain development and function, as well as better understanding the causes of neurodegenerative diseases and developing and improving therapeutic strategies.


Tuesday, 05 Feb 2019 16:00
Department of Neurosciences

Location: NC1-202
Title: "The reversible inhibition of hippocampal neurogenesis in a cuprizone-induced de- and remyelination model"
Hai Zhang, Ph.D., Laboratory of Dr. Hoonkyo Suh

Tuesday, 19 Feb 2019 16:00
Department of Neurosciences

Location: NC1-202
Title: "A novel biomaterial-based ischemic stroke model of rat"
Hiu Nam Chan, Ph.D., Laboratory of Dr. Andre Machado

A small and localized ischemic stroke model of rat is achieved by infusing a small dose of endothelin 1 (ET-1) into the targeted area, such as the motor cortex. The lesion size is determined by the number of injections of ET-1 created, which is a very time-consuming process. In this study, we developed a novel delivery mechanism of ET-1 by using biomaterials to achieve a quick procedure, but resulting in a more efficient ischemic model of stroke. The new stroke model was characterized behaviorally and histologically.


Wednesday, 20 Feb 2019 10:00
Department of Neurosciences

Location: NE1-205
Title: "Infection, autoimmunity and the brain: Lessons learned from rare diseases"
Tory P. Johnson, PhD, Assistant Professor of Neurology, Johns Hopkins University, School of Medicine

Hosted by Dr. Bruce Trapp


Wednesday, 06 Mar 2019 10:00
Department of Neurosciences

Location: NE1-205
Title: "Consequences of Microglial-Mediated Recruitment of Inflammatory Monocytes to the Brain with Psychological Stress"
Jonathan Godbout, PhD, Professor, Department of Neuroscience, Institute for Behavioral Medicine Research, Center for Brain and Spinal Cord Repair, The Ohio State University

Hosted by: Jessica Williams


Wednesday, 20 Mar 2019 10:00
Department of Neurosciences

Location: NE1-205
Title: "Thalamic MRI, histopathologic, and clinical correlations in multiple sclerosis"
Kedar R. Mahajan, MD, PhD, Associate Staff, Neurological Institute, Cleveland Clinic

Hosted by: Bruce Trapp