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Glen Taksler Research Program

❮Quantitative Health Sciences Glen Taksler Research Program
  • Glen Taksler Research Program
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Principal Investigator

Glen Taksler Headshot

Glen Taksler, PhD

Staff
Primary Appointment in Internal Medicine
Email: [email protected]
Location: Cleveland Clinic Main Campus

Research

Glen Taksler’s research aims to translate evidence-based medicine into clear priorities that guide patients, clinicians and health systems toward the interventions most likely to improve length and quality of life. He has developed methods to individualize preventive health care guidelines based on patient-specific risk factors and prioritize preventive services based on their potential to improve longevity.

Currently, Dr. Taksler is Principal Investigator of a study funded by the National Institutes of Health (National Institute on Aging) to help middle-aged adults make an informed decision about the primary preventive services that are most likely to promote a longer, healthier life. He also founded and leads an electronic health records-based registry of more than 1 million primary care patients.

Dr. Taksler’s other work includes analyzing population health, health information technology, and underlying causes of infant mortality. His methods include evidence-based medicine, economic analysis, observational study design using large datasets, and decision analytic and predictive risk modeling.

Dr. Taksler’s research has been funded by the National Institute on Aging, National Center for Advancing Translational Sciences, Clinical and Translational Science Collaborative of Cleveland and Dana-Farber Cancer Institute.


Biography

Glen Taksler is Associate Professor of Medicine at Cleveland Clinic Lerner College of Medicine; Staff at Cleveland Clinic’s Primary Care Institute and Cleveland Clinic’s Department of Quantitative Health Sciences; and Faculty at the Center for Health Care Research and Policy, Population Health Research Institute at Case Western Reserve University at The MetroHealth System. Dr. Taksler Co-Chairs the Education Committee of the Society for Medical Decision Making and is a member of the Research Committee of the Society of General Internal Medicine.

 Dr. Taksler has received national and regional awards, including the Best Overall Design by the Agency for Healthcare Research and Quality (AHRQ) Challenge on Designing the Optimal Future State of CDS Connect (with collaborators at the University of Michigan, 2024); Award for Excellence in Clinical Investigation by the Society of General Internal Medicine Midwest Region (2019); the Most Outstanding Paper by a Young Investigator Award by the Society for Medical Decision Making (2014); and the Milton W. Hamolsky Award for Most Outstanding Junior Faculty Abstract by the Society of General Internal Medicine (2014). 


Education & Professional Highlights

 KL2 Scholar – Case Western Reserve University School of Medicine Clinical and Translational Science Cleveland, OH 2018 

 Postdoctoral Fellowship – New York University School of Medicine Population Health and General Internal Medicine New York, NY 2013 

 PhD – Harvard University Economics Cambridge, MA 2002 

 AM – Harvard University Economics Cambridge, MA 1999 

 BA – Johns Hopkins University Economics and Mathematical Sciences Baltimore, MD 1997 

Research

Research

Our Team

Our Team

Publications

Selected Publications

View publications for Glen Taksler, PhD
(Disclaimer: This search is powered by PubMed, a service of the U.S. National Library of Medicine. PubMed is a third-party website with no affiliation with Cleveland Clinic.)


Le Phuc, Tatar Moosa, Dasarathy Srinivasan, Taksler Glen B, Deshpande Abhishek, Adekunle Olajide A, McCullough Arthur, Rothberg Michael B. Estimated Burden of Metabolic Dysfunction-Associated Steatotic Liver Disease in US Adults, 2020 to 2050. JAMA Netw Open. 2025. 39821400.

Johnson Joshua K, Hamilton Aaron C, Hu Bo, Fox Robert J, Hashmi Ardeshir, Siegmund Lee Anne, Taksler Glen B, Goto Toyomi, Stilphen Mary, Rothberg Michael B. Assisted ambulation to improve health outcomes for older medical inpatients (AMBULATE): study protocol for a randomized controlled trial. Trials. 2023. 37488588.

Taksler Glen. CBK model composition using paired web services and executable functions: A demonstration for individualizing preventive services. Learn Health Syst. 2023. 37066102.

Taksler Glen B, Le Phuc, Hu Bo, Alberts Jay, Rothberg Michael B. Personalized Disease Prevention (PDP): study protocol for a cluster-randomized clinical trial. Trials. 2022. 36273151.

Taksler Glen B, Hu Bo, DeGrandis Frederic, Rothberg Michael B. Effect of Individualized Preventive Care Recommendations vs Usual Care on Patient Interest and Use of Recommendations: A Pilot Randomized Clinical Trial. JAMA Netw Open. 2021. 34726747.

Dalton Jarrod E, Gunzler Douglas D, Jain Vardhmaan, Perzynski Adam T, Dawson Neal V, Einstadter Douglas, Tarabichi Yasir, Imrey Peter B, Lewis Michael, Kattan Michael W, Yao James, Taksler Glen, Berg Kristen A, Krieger Nikolas I, Kaelber David, Jehi Lara, Kalra Ankur. Mechanisms of socioeconomic differences in COVID-19 screening and hospitalizations. PLoS One. 2021. 34351971.

Taksler Glen B. Modeling Strategies to Optimize Cancer Screening in USPSTF Guideline-Noncompliant Women. JAMA Oncol. 2021. 33914025.

Taksler Glen B, Pfoh Elizabeth R, Martinez Kathryn A, Sheehan Megan M, Rothberg Michael B. Comparison of National Data Sources to Assess Preventive Care in the US Population. J Gen Intern Med. 2022. 33791937.

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