Research Seminars & Events

The Lerner emphasizes translational research that has the potential to improve patient care. Our scientists work closely with Cleveland Clinic physicians to transform groundbreaking discoveries made in the laboratory to the bedside. Our collaborative Research Centers of Excellence bring together scientific and clinical experts to solve problems seen in patients and accelerate discoveries into new treatments and cures.

March 2019 16

Friday, 01 Mar 2019 10:00
Department of Cardiovascular & Metabolic Sciences

Location: NC1-202
Title: Targeting Metabolic Vulnerabilities in Cancer

Katherine Aird Pennsylvania State University College of Medicine

Tuesday, 05 Mar 2019 16:00
Department of Neurosciences

Location: NC1-202
Title: "Mechanosensory function of Kindlin3 in microglia is crucial for retinal vascular patterning"

Tejasvi Dudiki, Ph.D., Laboratory of Dr. Tatiana Byzova

Our study demonstrates that microglia control vascular growth and patterning in retinas by altering its gene expression in response to its surrounding extra cellular matrix. Using microglia-specific genetic knockout and knock-in mouse models, we show that this process is orchestrated by Kindlin3, an intracellular integrin adaptor. Lack of Kindlin3 in microglia caused abnormal vascular patterning and excessive vascular growth, which is reminiscent of early stages of human retinal angiomatous proliferation.

Wednesday, 06 Mar 2019 10:00
Department of Neurosciences

Location: NE1-205
Title: Cancelled-to be rescheduled

Jonathan Godbout, PhD, Professor, Department of Neuroscience, Institute for Behavioral Medicine Research, Center for Brain and Spinal Cord Repair, The Ohio State University

Hosted by: Jessica Williams

Friday, 08 Mar 2019 08:00
Northeast Ohio Alcohol Center

Location: NA1-139
Title: Plugging leaks: Identifying targets to reverse molecular disruption of tight junctions by alcohol

Michael Koval, PhD Professor of Medicine, Emory University School of Medicine

Friday, 08 Mar 2019 10:00
Department of Cardiovascular & Metabolic Sciences

Location: NC1-202
Title: Immunity in response to colonization with the microbiota

Timothy Hand University of Pittsburgh-Children's Hospital of Pediatrics Assistant Professor

Tuesday, 12 Mar 2019 10:00
Department of Inflammation and Immunity

Location: NE1-205
Title: "Gender Differences in Severe Asthma"

Joe Zein, MD, Faculty update

Tuesday, 12 Mar 2019 16:00
Department of Neurosciences

Location: NC1-202
Title: Mechanisms of Blood Brain Barrier Disruption in Neuroinflammatory Disease

Nozha Borjini, Ph.D., Laboratory of Dr. Dimitrios Davalos

Wednesday, 13 Mar 2019 12:00
Department of Inflammation and Immunity

Location: NE1-205
Title: "Degradation of the Deubiquitinase Otulin by RIPA pathway Inhibits Viral Replication"

Rameez Raja - Sen Lab

Friday, 15 Mar 2019 08:00
Northeast Ohio Alcohol Center

Location: NA1-140
Title: "Lymphatics in the liver"

Yasuko Iwakiri, PhD. Associate Professor of Medicine, Yale University

Monday, 18 Mar 2019 12:00
Genomic Medicine Institute

Location: NE1-205
Title: Design and execution of the first polygenic risk study in epilepsy

Costin Leu, PhD - Lal Lab - Genomic Medicine Institute

Tuesday, 19 Mar 2019 10:00
Department of Inflammation and Immunity

Location: NE1-205
Title: "T cell Metabolism and Fueling Immunity"

Jeff Rathmell, PhD; Vanderbilt University

Hosted by Xiaoxia Li, PhD

Wednesday, 20 Mar 2019 10:00
Department of Neurosciences

Location: NE1-205
Title: "Thalamic MRI, histopathologic, and clinical correlations in multiple sclerosis"

Kedar R. Mahajan, MD, PhD, Associate Staff, Neurological Institute, Cleveland Clinic

Hosted by: Bruce Trapp

Wednesday, 20 Mar 2019 12:00
Department of Inflammation and Immunity

Location: NE1-205
Title: TBD

Darshana Poddar - Sen Lab

Monday, 25 Mar 2019 12:00
Genomic Medicine Institute

Location: NE1-205
Title: PTEN in cell fate decision; Case of neural stem cell

Masahiro Hitomi, M.D., PhD - Eng Lab - Genomic Medicine Institute

Tuesday, 26 Mar 2019 10:00
Department of Inflammation and Immunity

Location: NE1-205
Title: "Repairing the Glomerulus through Regeneration"

Stuart Shankland, MD, MBA, FRCP; Professor, Division of Nephrology Head at University of Washington - Seattle

Hosted by Leslie Bruggeman, PhD

Wednesday, 27 Mar 2019 12:00
Department of Inflammation and Immunity

Location: NE1-205
Title: TBD

Mike Cheung - Gupta Lab