Diversity & Inclusion Statement

Our lab is committed to creating and maintaining an environment in which all are welcome and respected - one that is inclusive of race, gender, faith, sexual orientation, ability, and socioeconomic status. We acknowledge that many identities are underrepresented in STEM and in academia, and that systemic racism and other discriminations create obstacles for students and postdocs. We strongly condemn behaviors and institutions that perpetuate these inequities, and we as a lab must act to dismantle the structural and systemic barriers to higher education.

Mission Statement

The mission of our lab is to create a space for students and postdocs to develop the skills necessary to be able to effectively question, research, and communicate scientific topics. We understand that differences will exist in the level of training, knowledge, personal circumstances, and life and career goals of lab members. As such, our goal is to provide an equitable academic opportunity while taking these conditions into account.

Principal Investigator

Jacob Scott, MD, DPhil

Staff, Departments of Translational Hematology and Oncology Research and Radiation Oncology
Associate Professor, School of Medicine, Case Western Reserve University
Associate Director for Data Science, Case Comprehensive Cancer Center
Adjunct Associate Professor, Department of Physics, Case Western Reserve University

I am a veteran of the US Navy submarine force turned academic physician-scientist. Our lab pursues research decomposing the complexity of cancer through mathematical modeling and the biological and clinical validation of these models. My educational background in physics, medicine, mathematics and engineering gives me a unique perspective on cancer and systems biology and I am able to communicate and collaborate with professionals across many disciplines. I have worked extensively on mathematical modeling of cancer evolution and treatment using a variety of models including evolutionary game theory, cellular automata, differential equations and Markov chains. My DPhil thesis focused on the role of heterogeneity, both genetic and microenvironmental, on cancer evolution and radiation response, and my laboratory’s focus is cancer evolution and therapy resistance. Since starting Theory Division, we have begun to diversify, and the lab now has a significant experimental component, conducting experimental evolution in cancer cell lines as well as bacteria. The combination of mathematics, experimental evolution and a clinical focus makes our laboratory stand out as one of the most interdisciplinary in the field of translational cancer evolution and evolutionary medicine. I am eager to use my distinct perspective to help advance this field to help cancer patients.

Staff

Olivia Beebe

Senior Research Technologist

Email | Bio


Jay Crump

Post-baccalaureate fellow

Email | Bio


Mina Dinh

Post-bac studying cancer evolution

Email | Twitter | Bio


Masahiro Hitomi, MD, PhD

Research staff studying therapeutic resistance in cancer cells

Email | Bio


Post-doctoral Fellows

Kyle Card, PhD

Post-doctoral fellow

Email | Twitter | Bio


Jeff Maltas, PhD

Post-doc in evolutionary biology

Email | Twitter | Bio


Steph Owen, PhD

Post-doctoral fellow

Email | Twitter | Bio


Dagim Shiferaw Tadele, PhD

Post-doctoral fellow

Email | Bio


Graduate students

Arda Durmaz

PhD candidate studying drug resistance

Email | Twitter | Bio


Jason Gray

Graduate student studying evolutionary dynamics

Email | Twitter | Bio


Dena Guo

Medical student

Email | Bio


Eshan King

MD/PhD candidate studying computational modeling of resistance

Email | Twitter | Website | Bio


Kristi Lin-Rahardja

PhD candidate

Email | Bio


Jessica Scarborough, PhD

MD-PhD candidate

Email | Twitter | Bio


Davis Weaver

MD-PhD candidate

Email | Twitter | Bio


Associated Junior Faculty

Andrew Dhawan, MD, DPhil

Neuro-oncology fellow

Email | Twitter | Bio


Kailin Yang, MD, PhD

Radiation oncology resident

Email | Bio


Roberto Vargas, MD

Clinical Assistant Professor

Email | Bio


Part-time students

Bezhou Feng

Medical student

Email | Bio


Emily Ho

Med student optimizing individualized radiation therapy

Email | Bio


Siamrut Patanavanich

Med student making sense of data

Email | Bio


Beck Pierce

Undergraduate researcher

Email | Bio


Eashwar Somasundaram

Med student studying cancer via topology

Email | Twitter | Bio


Zhiyuan Yu

Undergraduate Researcher

Email | Bio


Lab alumni (listed by date of departure)

Name Lab Role Current Position Current Institution contact
Drew Williamson, MD MD student researcher Clinical Informatics Fellow Harvard Medical School Email
Inom Mirzaev, PhD Post-doctoral Fellow Sr. Machine Learning Engineer Twitter Email
Elena Svenson Graduate student Scientific Community Manager Code Ocean
Erin McClure Research Technologist MD candidate University of Florida Email
Nara Yoon, PhD Post-doctoral Fellow Assistant Professor Adelphi University Email
Zahraa Al-Turaihi, MD Research Fellow Resident Physician, Radiology Einstein Medical Center
Emily Dolson, PhD Post-doctoral Fellow Assistant Professor Michigan State University Email
Artem Kaznatchev, PhD DPhil student Post-doctoral Fellow University of Pennsylvania
Geoff Sedor, MD MD student researcher Resident Physician Columbia
Nathan Farrokhian, MD MD student researcher Resident Physician Kansas University
Raoul Wadhwa, MD MD student researcher Medical Student Cleveland Clinic Learner COllege of Medicine
Patrick Ellsworth, MD MD student researcher Resident Physician Brigham and Women's Hospital
Nikhil Krishnan, MD MD student researcher PhD Candidate University of Cambridge
Vishhvaan Gopalakrishnan, MD MD student researcher Research Fellow Cleveland Clinic
Luka Opašić, MD, PhD Post-doctoral fellow Chief Data Officer Bulbitech AS Email
Linh Huynh, PhD PhD student Post-doctoral fellow University of Utah