Dr. Erdemir played a key role in developing 10 rules to ensure the credibility of healthcare-related computational simulation and models.
Computational modeling and simulation have long been used in research and engineering, and are increasingly employed to predict the origin and spread of diseases.
With the growing popularity of computational modeling and its role in shaping treatment and policy decisions, standardization protocols are needed to deal with the complexities of modern biomedicine. As such, the national, interdisciplinary Committee on Credible Practice of Modeling & Simulation in Healthcare has created a list of 10 rules to establish modeling credibility, encompassing reproducibility, validity, accountability and outreach. The list was published in the Journal of Translational Medicine.
Ahmet Erdemir, PhD, associate staff in the Department of Biomedical Engineering and founding co-chair and active member of the committee, is lead author of the article. “Computational modeling and simulation are driving healthcare decisions more than ever before,” Dr. Erdemir noted. “The need for credible and reliable execution and interpretation has taken on a new urgency.”
The list of rules from the committee and their descriptions are as follows:
“Computational modeling is an indispensable strategy for biomedical research, individualized clinical decision-making and medical training,” said Dr. Erdemir. “The power of simulations cannot be realized without establishing their dependability and reliability. This study establishes broadly applicable, discipline-agnostic and usable guidance for building, utilizing and interpreting healthcare-related computational models.”
This project was supported by the National Institutes of Health.
Image: In a synergistic project funded by the National Institutes of Health, Dr. Erdemir and collaborators have been investigating the "art" of modeling and simulation. Using the same data and targeting the same intention for simulations, five teams have been building knee joint models. The activities demonstrate the relevance of the Ten Rules of credible practice; in this case, testing competing implementations in knee joint modeling. (Image adapted from Erdemir et al., J Biomech Eng, 2019, 141, 0710021-07100210; https://doi.org/10.1115/1.4043346.)
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