Our Team
Reham Abdelwahab Hassan Ali, MD, PhD
Associate Staff
Director, Oncology Data Science Program
[email protected]
Tyler Alban, PhD
Assistant Staff
Director, Translational and Correlative Sciences Service
[email protected]
Timothy Chan, MD, PhD
Department Chair
Cancer Sciences
Chair, Global Center for Immunotherapy and Immuno-Oncology
Co-Director, National Center for Regenerative Medicine
Director, Case CCC Immuno-Oncology Program
Lab Profile
Adi Diab, MD
Staff
Co-Chair, CCF Melanoma Program, Taussig Cancer Center
Director of Cancer Research, CCAD Cancer Institute
Jos Melenhorst, PhD
Vice Chair, Center for Immunotherapy & Precision Immuno-Oncology
Director, Cell Therapy & Immuno-Engineering Program
[email protected]
Lab Profile
Natalie Silver, MD, MS, FACS
Associate Staff
Associate Staff, Otolaryngology, Head & Neck Institute
Lab Profile
Anand Dev Tiwari, PhD
Research Associate
Medicinal Chemist
[email protected]
I am contributing my chemistry synthetic skills to the development of myeloma/leukemia inhibitors and mutation suppressor drug synthesis. Through small molecule as epigenetic drug targeting the biological pathway that’s effects and help in the progress of the cancerous cell. We do have approach to develop the drug with nontoxic treatment of the cancer (A.D. Tiwari et. al 2021, Bioorg. Med. Chem., Blood Cancer Discovery, Cancers & Seminars in Hematology). The interaction mechanism of pharmacologically active small organic molecules and biological therapeutic targets are my area of interest as a synthetic chemist. In my postdoctoral training, I explored fluorescent pharmacophore molecules and radioisotopes labelled imaging molecule probe as diagnostic tool for myelin imaging in multiple sclerosis research areas. The pharmacological active molecules are relevant to cancer, antibacterial, antifungal, anti-inflammatory, epigenetic, and therapeutic targets. During my pre-doctoral and doctoral research studies, I synthesized organic/inorganic molecules for the inhibition of nuclear factor NF-kb (R.K. Sharma and A.D. Tiwari et. al. 2008, Bioorg. Med. Chem) as well as DNA interacting molecules (A.D. Tiwari et. al 2011, Spectrochimica Acta Part A). In my doctoral studies, I synthesized metal nano-particles embedded in chemically modified biopolymer chitosan for prospective application as drug vehicles (A.D. Tiwari, 2011, Intern. J. Bio. Macromol. & 2013, Carbohydrate Polymer). I gained synthetic chemistry experience in peptide synthesis with fluorescent and nonsteroidal anti-inflammatory (NSAIDs) as amino acid-drug conjugates from Professor Alan R Katritzky's research group at the University of Florida (A.D Tiwari et.al 2014, Synthesis & 2014, Org. Biomol. Chemistry). My contributions to the development of Novel radiolabeled 18F-Myelin imaging molecular probes for monitoring myelin change in in-vivo conditions for multiple sclerosis have also been well-documented (A.D. Tiwari et al., 2016, 2017, 2019 J. Med. Chem.). Find Dr. Tiwari on Google Scholar and LinkedIn.
