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Philip Ahern, PhD
The Ahern lab focuses on understanding the homeostasis between the intestinal immune system and gut microbiota, and how imbalances contribute to the development and exacerbation of inflammatory bowel disease.
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Bela Anand-Apte, MBBS, PhD
The Anand-Apte lab studies the basic molecular mechanisms of ocular neovascularization and the pathways that regulate breakdown of the blood-retinal barrier in diabetic retinopathy.
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Suneel Apte, MBBS, Dphil
The Apte lab studies extracellular matrix and proteases and their effects on various diseases, including Marfan syndrome and the acromelic dysplasias.
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Mark Aronica, MD
The Aronia lab researches the role of several components of the extracellular matrix in the development and pathogenesis of asthma.
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William Baldwin, MD, PhD
The Baldwin lab studies the mechanisms through which antibodies alter lymphocyte responses in endothelial cells, platelets and leukocytes in the context of vascular pathology.
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Cornelia Bergmann, PhD
The Bergmann lab explores how the immune system controls viral infections of the central nervous system.
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Vera Bonilha, PhD
The Bonilha lab studies aging in the retina and retinal pigment epithelium (RPE) and how age-related macular degeneration (AMD) pathology affects RPE cellular function.
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Jonathan Mark Brown, PhD
The Brown lab studies the interrelationship between diet, lipid metabolism and the development of chronic disease.
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Abhishek Chakraborty, PhD
The Chakraborty lab studies chromatin biology in the context of dysregulated activity of oxygen-dependent enzymes (or dioxygenase), such as the JumonjiC-family histone demethylases.
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Tim Chan, MD, PhD
The Chan lab is interested in precision immuno-oncology and the genomic basis of tumor development and treatment response.
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Feixiong Cheng, PhD
The Cheng lab develops and utilizes innovative network medicine methodologies and systems biology technologies to predict drug targets and identify mechanisms of human diseases.
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Jan Claesen, PhD
The Claesen lab aims to functionally characterize molecular mechanisms that control bacterial interspecies and microbe-host interactions in the human microbiome.
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Seth Corey, MD
The Corey lab focuses on pediatric hematology and diseases including Shwachman-Diamond syndrome (SDS).
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Margot Damaser, PhD
The Damaser lab studies regenerative medicine, tissue engineering and device development for pelvic floor dysfunction, including urinary and fecal incontinence and pelvic organ prolapse.
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Dimitrios Davalos, PhD
The Davalos lab studies the role that neuroimmune mechanisms play in brain function under physiological conditions and during neurological disease.
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Carol de la Motte, PhD
The de la Motte lab focuses on innate mechanisms of intestinal protection that lead to disease when dysregulated.
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Tara DeSilva, PhD
The DeSilva lab studies myelination, focusing on blocking immune cell infiltration into the central nervous system (CNS), protecting the CNS during infiltration and promoting regeneration of myelin.
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Donna Driscoll, PhD
The Driscoll lab researches how selenoproteins are synthesized and how this pathway is affected in selenium insufficiency.
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Charis Eng, MD, PhD
The Eng lab identifies and characterizes genes that cause susceptibility to inherited cancer syndromes, ellucidating their role in sporadic carcinogenesis and clinical utility in diagnosis and treatment.
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Serpil Erzurum, MD
The Erzurum lab studies the mechanisms that initiate and perpetuate lung inflammation and remodeling and ultimately lead to lung diseases such as asthma and pulmonary vascular disease.
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Robert Fairchild, PhD
The Fairchild lab studies the role of innate immune mechanisms and CD8+ T cells in contact hypersensitivity, as well as the role of inflammatory/signaling proteins in allograft inflammation and rejection.
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Linda Graham, MD
The Graham lab investigates bypass graft and arterial healing after balloon angioplasty and stenting.
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Stanley Hazen, MD, PhD
The Hazen lab studies the mechanisms through which inflammation contributes to diseases like atherosclerosis and asthma, and the link between gut microbes and cardiovascular disease.
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Ming Hu, PhD
The Hu lab works to develop novel statistical and machine learning methods for personalized medicine.
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Emina Huang, MD
The Huang lab seeks to define how elements of the epithelia and the surrounding microenvironment interact to promote progression to cancer, particularly colorectal cancer, or conversely, to mitigate the progression.
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Tae Hyun Hwang, PhD
The Hwang lab develops novel machine learning, artificial intelligence and computational/bioinformatics algorithms and tools to gain new insights into genetic/phenotypic variants of human disease
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Trine Jorgensen, PhD
The Jorgensen lab focuses on the effects of sex hormones on the immune system during initiation/progression of lupus-like disease and the specific role played by type I interferons.
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Jae Jung, PhD
The Jung lab investigates virus-induced cancers, including Kaposi’s sarcoma, coronaviruses and other emerging pathogens.
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Dennis Lal, PhD
The Lal lab focuses on discovering genes related to epilepsy syndromes, developing novel methods for interpreting missense variants and characterizing patient disease trajectories.
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Justin Lathia, PhD
The Lathia lab’s main interest is how cancer stem cells from malignant brain tumors interact with their surrounding microenvironment, which provides signals to preserve the malignancy of these cells and drive cancer progression, paying close attention to these mechanisms in the context of glioblastoma.
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Vinod Labhasetwar, PhD
The Labhasetwar lab studies nanotechnology for the detection and treatment of various diseases.
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Xiaojuan Li, PhD
The Li lab studies musculoskeletal imaging techniques for a range of orthopaedic and rheumatologic disorders.
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Xiaoxia Li, PhD
The Li lab investigates the signaling mechanisms in innate and adaptive immunity.
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Feng Lin, PhD
The Lin lab is interested in studying complement system activation and regulation in innate immunity.
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Antoine Louveau, PhD
The Louveau lab investigates the role of the meninges in normal and pathological brain function to identify therapeutics for neurological disorders that target the meningeal compartment.
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Michelle Longworth, PhD
The Longworth lab investigates how changes to DNA organization within the nucleus of a cell impact development and disease.
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Omar Mian, MD, PhD
The Mian lab explores the genetic and epigenetic mechanisms underlying lethal cancers of the genitourinary tract with the goal of translating discovery in to novel therapies.
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Ignacio Mata, PhD
The Mata lab studies genes that impact neurological disorders, including Parkinson’s disease, with a particular focus on underrepresented populations, especially Latinos.
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Christine McDonald, PhD
The McDonald lab investigates immune response control and how alterations in these responses contribute to the development of Crohn’s disease.
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Laura Nagy, PhD
The Nagy lab studies how chronic alcohol consumption contributes to diseases such as liver disease and diabetes.
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Christine OConnor, PhD
The O’Connor lab researches cytomegalovirus infection, pathogenesis and disease.
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Richard Padgett, PhD
The Padgett lab focuses on mechanisms of post-transcriptional RNA processing, particularly pre-mRNA splicing.
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Brian Perkins, PhD
The Perkins lab investigates photoreceptor degeneration and regeneration.
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Ela Plow, PhD, PT
The Plow lab studies the potential of rehabilitation, movement re-learning and noninvasive brain stimulation to prevent or promote recovery following brain injury, including stoke.
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Sujata Rao, PhD
The Rao lab is interested in understanding how neurons and vasculature pattern themselves and interact with each other during development as well as in disease.
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Ofer Reizes, PhD
The Reizes lab studies pathways related to the development and pathogenesis of women’s cancers, including triple negative breast cancer and gynecologic cancers, to develop novel targeted therapies.
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Brian Rubin, MD, PhD
The Rubin lab seeks to understand the pathogenesis of bone and soft tissue cancers, collectively known as sarcomas.
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Yogen Saunthararjah, MD
The Saunthararjah lab works to develop therapies that selectively destroy malignant cells while sparing normal stem cells, searching for alternatives to traditional therapies like chemo- and radiation therapy.
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Jacob Scott, MD, DPhil
The Scott lab uses mathematical and experimental models to help increase the efficacy of targeted therapies and radiation for cancers.
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Sarah Schumacher-Bass, PhD
The Schumacher-Bass lab studies the mechanisms that underlie the transition from adaptive to adverse vascular remodeling, including changes in cardiac structure, function, metabolism, fibrosis and arrhythmogenesis.
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Nima Sharifi, MD
The Sharifi lab studies fundamental metabolic processes that govern prostate cancer progression.
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Jonathan Smith, PhD
The Smith lab applies principles of cell/molecular biology, biochemistry and genetics/genomics to study cardiovascular diseases, including atherosclerosis, atrial fibrillation and lipid metabolism
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Thaddeus Stappenbeck, MD, PhD
The Stappenbeck lab researches host and environmental factors that impact inflammation and wound repair, which influence the pathogenesis of diseases including inflammatory bowel disease.
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George Stark, PhD
The Stark lab studies the complex interactions of cells in innate immunity and cancer
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Olga Stenina Adognravi, PhD
The Stenina Adognravi lab studies the vascular complications of diabetes.
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Angela Ting, PhD
The Ting lab examines the mechanisms of epigenetic gene silencing and the functional relevance of DNA methylation in cancer.
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Bruce Trapp, PhD
The Trapp lab explores the cause of permanent neurological disability in multiple sclerosis (MS) and focuses on pathological and molecular changes in postmortem MS brains.
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Anna Valujskikh, PhD
The Valujskikh lab investigates the functions of graft-reactive memory CD4 T cells in organ transplant, with the ultimate goal to develop combinatorial therapies for sensitized transplant recipients.
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Lily Wang, PhD
The Wang lab seeks to define the mechanisms by which immune checkpoint proteins regulate anti-tumor immune responses and to develop novel therapeutics for cancer immunotherapy
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Oliver Wessely, PhD
The Wessely lab studies the molecular mechanisms governing kidney formation and maintenance and how these processes are perturbed during kidney diseases
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Jessica Williams, PhD
The Williams lab investigates the interplay between the immune and central nervous systems during multiple sclerosis (MS) in order to uncover novel therapeutic options for MS patients
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Alex Yuan, MD, PhD
The Yuan lab’s primary goal is to characterize the retina’s wound healing and regenerative responses in order to develop novel methods for retinal repair.
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